… with clinically isolated syndrome suggestive of multiple sclerosis. Sixty-three patients were
studied 30 years after their initial presentation with a clinically isolated syndrome… , grey matter …

… who presented with a clinically isolated syndrome suggestive … brain regional atrophy within
5 years of a clinically isolated … ,28 and significantly smaller grey matter volumes reported in …

… To support information presented at the workshop and data … Several biomarkers evaluated
in clinically isolated syndrome (… /Cr ratio in mid-parietal gray matter. A trend toward lower NAA …

… definite MS in patients with clinically isolated syndrome (CIS) [4]. Atrophy of the grey matter
(GM… To this end, the presented results provide a priori regions of interest for testing as well as …

… matter (WM) lesions and accelerated regional and global … In this study, patients presenting
with CIS were followed over a … between WM lesions and gray matter (GM) atrophy. However, …

… on MRI upon first clinical presentation, suggesting that many … periventricular regions and
even within the posterior fossa, … diagnosed with clinically isolated syndrome or multiple sclerosis…

… depression symptoms and white matter volume is related to … correlate with atrophy of cortical
and subcortical gray matter [… white and gray matter in frontal and temporal regions assessed …

… ), white matter volume (nWMV), gray matter … presented here should be supported with
further studies. In conclusion, we showed that neurodegeneration in the papillomacular region of …

… The thalamus is a key deep gray matter (GM) structure involved in motor planning, sensory
… stages of MS, in patients presenting with a clinically isolated syndrome (CIS). In addition to …

… of patients to a diagnosis of clinically isolated syndrome is presented in Figure 3. Patients …
syndrome because CC is the largest white matter bundle, which connects cortical regions …