… that regulate B cell differentiation to both promote long-lived … Therefore, in order for B cells
to transition into cellular Ig … in marginal zone B cells but not follicular B cells. This defect in …

… We discuss the regulatory effects of Tfr cells on B cell proliferation and the germinal center
response. … Then, we delve into the mechanisms that Tfr cells regulate GC B cells. Tfr …

… located inside B-cell follicles within secondary … ), follicular dendritic cells (FDCs) that present
Ag in the form of immune complexes to GC B cells (3), and T follicular helper (Tfh) cells. CCs …

… Within the GC, B cells capture antigen from follicular … In the context of cellular heterogeneity
of GC B cells, … initiate and control the transition and progression of the activated B cell toward …

… LZ follicular B GC -cells than on DZ B GC -cells (4, 20). In addition, B cell differentiation into
PCs … for Monocle-ordered cells showing a sequential transition from LZ B GC -cells to PBs for …

… , GC B cells compete for signals from T follicular helper cells (… to the regulation of these key
factors in GC B cell differentiation. … GC B cells, facilitating DZ to LZ transition of GC B cells and …

… B cell migration to and positioning within the follicles are guided … Little is known about the
role of IL-10-producing regulatory B cells … beyond the transitional stage 1 of development (72). …

… into follicular B (FOB) and marginal zone B (MZB) cells. … will focus on the regulation of
important processes during the … a fraction of BM transitional B cells differentiate into B-1 cells. …

… MZ B cells, we also fed Tsc1 fl/fl CD20-TAM-Cre and control … of follicular or MZ B cells, nor
in their plasma cell induction … as transitional B cells mature into follicular B cells (55). Thus, …

… Therefore, it significantly improves our capacity to analyze dynamic changes within the
cell during its transition from one state to another. However, quantification of RNA transcripts …