Follicular helper and follicular regulatory T cell subset imbalance is associated with higher activated B cells and abnormal autoantibody production in primary anti …
Y Long, W Li, J Feng, Y Ma, Y Sun, L Xu… - Clinical & …, 2021 - academic.oup.com
… memory B cells and CD24 hi CD38 hi transitional B cells between the two groups (Figure
3a,… caused by T cell hyperactivity and B cell over-stimulation, resulting in over-production of …
3a,… caused by T cell hyperactivity and B cell over-stimulation, resulting in over-production of …
Altered circulating follicular T helper cell subsets and follicular T regulatory cells are indicators of a derailed B cell response in lupus, which could be modified by …
K Szabó, I Jámbor, K Pázmándi, N Nagy… - International Journal of …, 2022 - mdpi.com
… Furthermore, we found a significant increase in the percentages of transitional B cells in SLE
… + B cells and CD4 + CXCR5 + T cells during in vitro experiments, but not sorted cT FH and …
… + B cells and CD4 + CXCR5 + T cells during in vitro experiments, but not sorted cT FH and …
T follicular cells: The regulators of germinal center homeostasis
… contribute to ensuring the production of high-affinity antibodies by GC B cells during an
immune response are named T follicular helper (Tfh) and T follicular regulatory (Tfr) cells. Tfh …
immune response are named T follicular helper (Tfh) and T follicular regulatory (Tfr) cells. Tfh …
Specific induction of double negative B cells during protective and pathogenic immune responses
…, GP Owens, JL Bennett, B Hemmer… - Frontiers in …, 2020 - frontiersin.org
… When looking at DN B cells on a subject level, we found a down-regulation of CXCR5
transcripts … Further indirect evidence for extra-follicular DN maturation derives from the clonal …
transcripts … Further indirect evidence for extra-follicular DN maturation derives from the clonal …
Aberrant B cell signaling in autoimmune diseases
OBJ Corneth, SFH Neys, RW Hendriks - Cells, 2022 - mdpi.com
… recent new immigrant B cells, called transitional B cells, in the … T cell subset that controls GC
B cell selection is the follicular … to control central B cell tolerance and to be dysregulated in B …
B cell selection is the follicular … to control central B cell tolerance and to be dysregulated in B …
T follicular regulatory cells: choreographers of productive germinal center responses
… in which Tfr cells regulate antigen-specific B cell responses. … parallel, other B cells migrate
back into follicle to seed early … with the former a transitional phenotype potentially because of …
back into follicle to seed early … with the former a transitional phenotype potentially because of …
Germinal center reaction
C Huang - B Cells in Immunity and Tolerance, 2020 - Springer
… -affinity B cell selection and the molecular control of these … B cells in the B cell follicles
and CD4 + T cells in the T cell … The mutations are non-random; transitions dominate over …
and CD4 + T cells in the T cell … The mutations are non-random; transitions dominate over …
Intrinsic and extrinsic regulation of IgE B cell responses
AK Wade-Vallance, CDC Allen - Current opinion in immunology, 2021 - Elsevier
… lymphocytes in mice reported that IgE B cells were unusual in that a large proportion differentiated
into IgE plasma cells … In general, T follicular regulatory (T FR ) cells that co-express Bcl-…
into IgE plasma cells … In general, T follicular regulatory (T FR ) cells that co-express Bcl-…
The amount of BCL6 in B cells shortly after antigen engagement determines their representation in subsequent germinal centers
… of B cell activation, culminating in preferential transition into GC. … in GC over several weeks;
other BCL6-regulated GC B cell … DZ recycling or follicle egress based on their B cell receptor …
other BCL6-regulated GC B cell … DZ recycling or follicle egress based on their B cell receptor …
Plasma cells: from cytokine production to regulation in experimental autoimmune encephalomyelitis
AA Wang, JL Gommerman, OL Rojas - Journal of molecular biology, 2021 - Elsevier
… transitional B cells, which will complete their maturation in the spleen to generate follicular
(FO) B-2 cells (… regulatory B cells which modulate EAE-associated inflammation [73]. Mice with …
(FO) B-2 cells (… regulatory B cells which modulate EAE-associated inflammation [73]. Mice with …