STAT3 signaling in B cells controls germinal center zone organization and recycling

AJ Fike, SB Chodisetti, NE Wright, KN Bricker… - Cell reports, 2023 - cell.com
… proliferation and SHM of Ig genes, differentiate into long-lived plasma cells (LL-PCs) or
memory B cells (MBCs), or undergo apoptosis. Regulation of the GC DZ and LZ is important for …

Single-cell transcriptomic analyses define distinct peripheral B cell subsets and discrete development pathways

A Stewart, JCF Ng, G Wallis, V Tsioligka… - Frontiers in …, 2021 - frontiersin.org
… order to evaluate the dynamic transitions between B cell clusters. This … B cells can also be
regulatory, producing IL10 and ensuring … of B cell development that appear to separate into T …

B cell residency but not T cell–independent IgA switching in the gut requires innate lymphoid cells

M Zheng, K Mao, D Fang, D Li, J Lyu… - Proceedings of the …, 2021 - National Acad Sciences
… interaction between T follicular helper cells and B cells (13, … play an important role in the
regulation of IgA production in the … recruited into the gut and differentiate into IgA + plasma cells

The special unfolded protein response in plasma cells

D Ricci, T Gidalevitz, Y Argon - Immunological reviews, 2021 - Wiley Online Library
… build a plasma cell: Integrating gene regulatory networks with … into follicular, marginal zone,
and B1 cells, with the follicular … The transition of pre-B cells to immature B cells involves a …

[HTML][HTML] Profiling circulating T follicular helper cells and their effects on B cells in post-cardiac transplant recipients

Y Wang, Z Liu, J Wu, F Li, G Li… - Annals of Translational …, 2020 - ncbi.nlm.nih.gov
… the levels of circulating T follicular regulatory cells (cTfr), which … of naïve B cells and transitional
B cells in CD19 + B cells was … and B cells into lymph nodes (37,38). The concentration of …

Requirements of IL-4 during the Generation of B Cell Memory

CR Chakma, KL Good-Jacobson - The Journal of Immunology, 2023 - journals.aai.org
… Tfh cells during Th2 cell–biased humoral immune responses (63, … -4–producing T cells in
B cell follicles are Tfh cells, similarly … on humoral responses and regulate different B cell fates. …

Diverging regulation of Bach2 protein and RNA expression determine cell fate in early B cell response

Q Hu, T Xu, M Zhang, H Zhang, Y Liu, H Li, C Chen… - Cell reports, 2022 - cell.com
… to the periphery of B cell follicles and interfollicular zones of secondary lymphoid organs,
where they form cognate interactions with T follicular helper (Tfh) cells within 1–3 days ( …

How intrinsic and extrinsic regulators of plasma cell survival might intersect for durable humoral immunity

MJ Robinson, RH Webster… - Immunological reviews, 2020 - Wiley Online Library
… is determined during formation versus being regulated extrinsically … In the first days of an
immune response, follicular B cells follow … One of the key transitions in this process requires the …

Protein kinase CK2 regulates B cell development and differentiation

H Wei, W Yang, H Hong, Z Yan, H Qin… - The Journal of …, 2021 - journals.aai.org
… of transitional B cells, without changes in follicular B cells. … regulate B cell development and
differentiation, we first examined CK2α, CK2β, and CK2α′ expression patterns during B cell

B Cell composition is altered after kidney transplantation and transitional B cells correlate with SARS-CoV-2 vaccination response

…, P Schemmer, H Sourij, P Eller, B Prietl… - Frontiers in …, 2022 - frontiersin.org
… Additionally, 0.5 × 10 6 cells served as an unstained control. … MMF was highly prevalent in
our cohort (91.5% at T2), yet … BCs, ie, activated mBCs with a follicular origin (12). DN2 BCs …