[HTML][HTML] Integrins modulate extracellular matrix organization to control cell signaling during hematopoiesis
… that control hematopoiesis remains to be resolved. Here, we show … integrins play a key role
during fly hematopoiesis in regulating cell signals that control the behavior of hematopoietic …
during fly hematopoiesis in regulating cell signals that control the behavior of hematopoietic …
Fibronectin and its receptors in hematopoiesis
F Wirth, A Lubosch, S Hamelmann, IA Nakchbandi - Cells, 2020 - mdpi.com
… of integrins in hematopoiesis followed by a discussion of the effects of fibronectin and
fibronectin-binding receptors on … The differentiation of hematopoietic stem cells is tightly regulated, …
fibronectin-binding receptors on … The differentiation of hematopoietic stem cells is tightly regulated, …
Activation and suppression of hematopoietic integrins in hemostasis and immunity
MA Nolte, C Margadant - Blood, The Journal of the American …, 2020 - ashpublications.org
… In recent years, a large body of structural, biochemical, cell-biological, and animal studies
have provided novel insights into the regulation of hematopoietic integrins and greatly …
have provided novel insights into the regulation of hematopoietic integrins and greatly …
[HTML][HTML] “Caught in the net”: the extracellular matrix of the bone marrow in normal hematopoiesis and leukemia
C Zanetti, DS Krause - Experimental hematology, 2020 - Elsevier
… Inhibition of integrins α5β 1 … In drosophila, integrins regulate hematopoiesis and the
postinfection immune response via organization of the ECM and its density via the bone …
postinfection immune response via organization of the ECM and its density via the bone …
Erythropoiesis
CS Olver - Schalm's Veterinary Hematology, 2022 - Wiley Online Library
… into hemoglobinized RBCs. In normal animals, erythropoiesis and RBC mass are regulated
… to the immunoglobulin superfamily of adhesion receptors, and is predominantly expressed …
… to the immunoglobulin superfamily of adhesion receptors, and is predominantly expressed …
[HTML][HTML] A sticky wicket: defining molecular functions for CD34 in hematopoietic cells
… and thereby regulate cell shape, motility, and adhesion—all purported CD34-meditated
functions. In hematopoietic cell lines, CrkL enhances integrin-mediated adhesion to fibronectin …
functions. In hematopoietic cell lines, CrkL enhances integrin-mediated adhesion to fibronectin …
Niche-mediated integrin signaling supports steady-state hematopoiesis in the spleen
SH Mehatre, IM Roy, A Biswas, D Prit… - The Journal of …, 2021 - journals.aai.org
… population of HSCs, the functional regulation of which is not clearly … into spleen, similar
to the BM, was shown to be mediated via interaction of HSCs with their niche through integrins …
to the BM, was shown to be mediated via interaction of HSCs with their niche through integrins …
Biomechanical cues as master regulators of hematopoietic stem cell fate
H Li, Q Luo, W Shan, S Cai, R Tie, Y Xu, Y Lin… - Cellular and Molecular …, 2021 - Springer
… interwoven effects control hematopoiesis and … control epigenetic transcription [45]. In
leukemia cells, the absence of cytoskeletal mechanical tension and subsequent weak adhesion to …
leukemia cells, the absence of cytoskeletal mechanical tension and subsequent weak adhesion to …
Molecular regulation of hematopoietic stem cell quiescence
Z Chen, Q Guo, G Song, Y Hou - Cellular and Molecular Life Sciences, 2022 - Springer
… , undergoing proliferation and differentiation into hematopoietic stem/progenitor … regulatory
networks of HSC quiescence, providing deep insight into HSC hemostasis and hematopoiesis…
networks of HSC quiescence, providing deep insight into HSC hemostasis and hematopoiesis…
β4GALT1 controls β1 integrin function to govern thrombopoiesis and hematopoietic stem cell homeostasis
S Giannini, MM Lee-Sundlov, L Rivadeneyra… - Nature …, 2020 - nature.com
… control) throughout week 1–16 post-transplant (Fig. 3f). By contrast, transplanted GFP + control
hematopoietic progenitor cells transplanted into … We first tested the adhesion of platelets …
hematopoietic progenitor cells transplanted into … We first tested the adhesion of platelets …