[HTML][HTML] Integrins modulate extracellular matrix organization to control cell signaling during hematopoiesis

RJ Khadilkar, KYL Ho, B Venkatesh, G Tanentzapf - Current Biology, 2020 - cell.com
… that control hematopoiesis remains to be resolved. Here, we show … integrins play a key role
during fly hematopoiesis in regulating cell signals that control the behavior of hematopoietic

Fibronectin and its receptors in hematopoiesis

F Wirth, A Lubosch, S Hamelmann, IA Nakchbandi - Cells, 2020 - mdpi.com
… of integrins in hematopoiesis followed by a discussion of the effects of fibronectin and
fibronectin-binding receptors on … The differentiation of hematopoietic stem cells is tightly regulated, …

Activation and suppression of hematopoietic integrins in hemostasis and immunity

MA Nolte, C Margadant - Blood, The Journal of the American …, 2020 - ashpublications.org
… In recent years, a large body of structural, biochemical, cell-biological, and animal studies
have provided novel insights into the regulation of hematopoietic integrins and greatly …

[HTML][HTML] “Caught in the net”: the extracellular matrix of the bone marrow in normal hematopoiesis and leukemia

C Zanetti, DS Krause - Experimental hematology, 2020 - Elsevier
… Inhibition of integrins α5β 1 … In drosophila, integrins regulate hematopoiesis and the
postinfection immune response via organization of the ECM and its density via the bone …

Erythropoiesis

CS Olver - Schalm's Veterinary Hematology, 2022 - Wiley Online Library
into hemoglobinized RBCs. In normal animals, erythropoiesis and RBC mass are regulated
… to the immunoglobulin superfamily of adhesion receptors, and is predominantly expressed …

[HTML][HTML] A sticky wicket: defining molecular functions for CD34 in hematopoietic cells

MR Hughes, DC Hernaez, J Cait, I Refaeli, BC Lo… - Experimental …, 2020 - Elsevier
… and thereby regulate cell shape, motility, and adhesion—all purported CD34-meditated
functions. In hematopoietic cell lines, CrkL enhances integrin-mediated adhesion to fibronectin …

Niche-mediated integrin signaling supports steady-state hematopoiesis in the spleen

SH Mehatre, IM Roy, A Biswas, D Prit… - The Journal of …, 2021 - journals.aai.org
… population of HSCs, the functional regulation of which is not clearly … into spleen, similar
to the BM, was shown to be mediated via interaction of HSCs with their niche through integrins

Biomechanical cues as master regulators of hematopoietic stem cell fate

H Li, Q Luo, W Shan, S Cai, R Tie, Y Xu, Y Lin… - Cellular and Molecular …, 2021 - Springer
… interwoven effects control hematopoiesis and … control epigenetic transcription [45]. In
leukemia cells, the absence of cytoskeletal mechanical tension and subsequent weak adhesion to …

Molecular regulation of hematopoietic stem cell quiescence

Z Chen, Q Guo, G Song, Y Hou - Cellular and Molecular Life Sciences, 2022 - Springer
… , undergoing proliferation and differentiation into hematopoietic stem/progenitor … regulatory
networks of HSC quiescence, providing deep insight into HSC hemostasis and hematopoiesis

β4GALT1 controls β1 integrin function to govern thrombopoiesis and hematopoietic stem cell homeostasis

S Giannini, MM Lee-Sundlov, L Rivadeneyra… - Nature …, 2020 - nature.com
control) throughout week 1–16 post-transplant (Fig. 3f). By contrast, transplanted GFP + control
hematopoietic progenitor cells transplanted into … We first tested the adhesion of platelets …