… the context of in vitro and in vivo models of organ injury and disease [11,24]… HO-1 may regulate
heme bioavailability in these … to hyperoxia, and reduced histological indices of lung injury, …

… of hyperoxia-induced lung injury in BPD involved pulmonary … of heme oxygenase-1 (HO-1)
in lung epithelial cells of … enzyme to reduce the oxygen free radicals in vivo (25,26). HO-1 and …

… ) or their exosomes on hyperoxia-induced lung injury have been … The protective response
regulated by HO-1 has been … responses by activating heme oxygenase-1 expression and the …

… Heme oxygenase-1, a vital heme degradative enzyme and … activity, specifically via the
transcriptional regulation of HO-1, … Acute lung injury (hyperoxia): Anti-inflammatory effects were …

… factor regulating the expression of heme oxygenase-1 (HO-1)… -1 and down-regulated the
protein expression of BACH1 in a … Furthermore, we performed in vitro experiments using …

… species: heme oxygenase-1 (HO-1) and heme oxygenase-2 (HO-… Heme causes vascular
permeability in vivo and activates … to hyperoxia, and reduced histological markers of lung injury, …

… Given that DEX has been clinically used for its sedation and analgesia, the advancing
knowledge we have provided here on the regulation of mitochondrial dynamics of DEX via …

… response, including the heme oxygenase-1/carbon monoxide … for the treatment of CF lung
disease. Finally, we discuss … In vitro and ex vivo studies from patients with CF and animal …

… effects of heme oxygenase-1 (HO-1) on lung injury (LI) after … mechanisms, and preclinical
data in vivo should be studied. So, … in rats with hyperoxia-induced acute lung injury. Zhonghua …

… exposed male C57BL/6 mice and heme oxygenase-1 (HO-1)-… Taken as a whole, these in
vivo and in vitro data show that … (LPS) [26–28], hyperoxia [29] and other forms of oxidative stress…