… cells by upregulation of p53 expression and initiation of the … , bromelain inhibits nuclear
factor-κB (NF-κB) translocation via … of bromelain decreased the levels of cyclooxygenase-2 (COX…

… Expression of proapoptotic proteins ie Bax, Bad, cytochrome c, and p53 and antiapoptotic
… We found that in only DLA cells, the expression level of Bax, Bad, Cytochrome c, and p53 is …

… 2 expression and augments proapoptotic factors like (p53 and … All these could regulate
the MAPK and Akt/PKB pathways, … the critical transcription factors (STAT-3, COX-2 and NF-κB) …

… through the activation of NF-kB(nuclear factor-kappa B). [19]. Cyclooxygenase-2 (COX-2)
expression is regulated by … in mouse skin papillomas by upregulating p53 and Bax, followed by …

… Bromelain has been shown to prevent nuclear factor αB (NF-… cancer cells by upregulating
the expression of p53, and the … -associated inflammation, cyclooxygenase-2 is involved in …

… This is the case of cyclooxygenase-2 (Cox-2) or the MAPK and … that bromelain regulates
p53, NF-kB, and COX-2 expression … to the gene expression of some nuclear factors (poly ADP …

… of p53, shifts in the reduction in cyclooxygenase-2 (COX-2) … By preventing the activation
of MAPK-regulated NF-κB, which … effect of bromelain using tumor mice model via Ki-67 and …

… the expression of COX-2 and nuclear factor κB (NF-κB). At … induction of p53, shifts in the
decreases in Cox-2 expression, … and inhibition of the NF-κB pathway through regulation of the …

… (PARP1), nuclear factor kappa activated B cells (NF-κB), and … and NF-κB expression compared
to control group and a … It may also be due to the BL enhancement of p53 expression, as …

… also presented smaller levels of cyclooxygenase-2 (COX-2), … and the up-regulation of p53,
Bax and proapopitotic proteins, … , such as pineapple pulp bromelain, presented the lowest …