Detection techniques of carboxylesterase activity: An update review

L Lan, X Ren, J Yang, D Liu, C Zhang - Bioorganic chemistry, 2020 - Elsevier
… Taking into account the crucial role of CESs in both endobiotic and xenobiotic metabolism, …
This review summarizes the development and application of CESs detection techniques in …

Carboxylesterase inhibitors from clinically available medicines and their impact on drug metabolism

YQ Song, Q Jin, DD Wang, J Hou, LW Zou… - Chemico-Biological …, 2021 - Elsevier
carboxylesterases (CES) are one important class of serine hydrolases that break down
numerous endogenous substances and xenobiotics … a αβ domain and a regulatory domain. The …

Biochemical activation and functions of drug-metabolizing enzymes

A Shabbira, K Haiderb, K Rehmanc… - Biochemistry of Drug …, 2022 - books.google.com
Drug-metabolizing enzymes (DMEs) are the diverse group of enzymes that are involved in
the biotransformation reactions of a vast variety of xenobiotics (Penner, Woodward, & Prakash…

Esterase is a powerful tool for the biodegradation of pyrethroid insecticides

P Bhatt, K Bhatt, Y Huang, Z Lin, S Chen - Chemosphere, 2020 - Elsevier
… Esterases belong to hydrolase enzyme family and play critical regulatory roles in pyrethroid
… Main function of carboxylesterases is the degradation of pyrethroids and other xenobiotics

Biochemical activation and functions of drug-metabolizing enzymes

A Shabbir, K Haider, K Rehman, MSH Akash… - Biochemistry of Drug …, 2022 - Elsevier
Drug-metabolizing enzymes (DMEs) perform a crucial role in the metabolism of xenobiotics,
especially the drugs. These DMEs also lead to the conversion of prodrugs into their active …

Transport and Metabolism of Xenobiotics in the Urban Ecosystem

S Paul, U Ghosh, M Saha - Xenobiotics in Urban Ecosystems: Sources …, 2023 - Springer
… with xenobiotic metabolism as well as removal. Upon introduction of xenobiotics from different
… Finally, a detailed overview of the transport of xenobiotic compounds and their metabolism …

The role of carboxylesterase enzymes in Capecitabine therapy

S Stoeva, N Conev, P Marinov - Scripta Scientifica …, 2020 - journals.mu-varna.bg
Introduction: Capecitabine (CAP) is an oral antineoplastic pro-drug, whose initial step of
activation is carboxylesterase (CES) dependent. The main conversion of CAP to 5-DFCR occurs …

Drug metabolism: Detoxification and xenobiotic biotransformation

J Surendradoss, A Varghese, S Deb - Biologically Active Small …, 2023 - taylorfrancis.com
… , and brain, which are rich in carboxylesterases and various other esterases mentioned
above.… The literature review suggests that AhR is chiefly engaged in the regulation of the CYP1 …

[HTML][HTML] Probiotics as a biological detoxification tool of food chemical contamination: A review

P Średnicka, E Juszczuk-Kubiak, M Wójcicki… - Food and Chemical …, 2021 - Elsevier
review aims to summarize the current knowledge of the direct mechanisms by which
probiotics can influence the detoxification of xenobiotics… practices requirements which do not …

Comparative analysis of the detoxification gene inventory of four major Spodoptera pest species in response to xenobiotics

D Amezian, R Nauen, G Le Goff - Insect Biochemistry and Molecular …, 2021 - Elsevier
review (induced by xenobiotics or in resistant populations). The four ecdysteroidogenic
genes CYP302, CYP314, CYP315, CYP306, involved in the biosynthesis of molting hormones (…