The role of G protein-coupled receptor kinase 4 in cardiomyocyte injury after myocardial infarction
L Li, W Fu, X Gong, Z Chen, L Tang… - European Heart …, 2021 - academic.oup.com
… have identified complex signal transduction processes regulating cardiomyocyte death,
but … GRK4 aggravates cardiac ischemic injury via inhibiting autophagy in a HDAC4-dependent …
but … GRK4 aggravates cardiac ischemic injury via inhibiting autophagy in a HDAC4-dependent …
Mitochondrial remodeling and ischemic protection by G protein–coupled receptor 35 agonists
… protects isolated hearts against ischemia, we focused on the aryl hydrocarbon receptor (AhR)
and G protein… 24 hours before injury in vivo or 10 or 30 min before I/R in ex vivo hearts was …
and G protein… 24 hours before injury in vivo or 10 or 30 min before I/R in ex vivo hearts was …
Heat shock protein 70 protects the heart from ischemia/reperfusion injury through inhibition of p38 MAPK signaling
N Song, J Ma, X Meng, H Liu, H Wang… - Oxidative Medicine …, 2020 - Wiley Online Library
… with p38 MAPK signaling is unclear. Therefore, this study investigated the regulation of p38
MAPK by … role of Hsp70 and its regulation of p38 MAPK signaling during I/R-induced cardiac …
MAPK by … role of Hsp70 and its regulation of p38 MAPK signaling during I/R-induced cardiac …
The role of pyroptosis in ischemic and reperfusion injury of the heart
SV Popov, LN Maslov, NV Naryzhnaya… - Journal of …, 2021 - journals.sagepub.com
… ischemic rabbit, rat, and monkey hearts and protect by the same signal transduction
pathway as ischemic … and what are the endogenous regulators of the heart’s vulnerability to …
pathway as ischemic … and what are the endogenous regulators of the heart’s vulnerability to …
Remote ischemic preconditioning induces cardioprotective autophagy and signals through the IL-6-dependent JAK-STAT pathway
M Billah, A Ridiandries, UK Allahwala… - International Journal of …, 2020 - mdpi.com
… can protect the heart from I/R injury by upregulating the JAK-STAT … acute ischemic injury
also causes myocardial injury [100], this study focused on the effect of autophagy regulation on …
also causes myocardial injury [100], this study focused on the effect of autophagy regulation on …
[HTML][HTML] Ginsenoside Rb1 attenuates cardiomyocyte apoptosis induced by myocardial ischemia reperfusion injury through mTOR signal pathway
CY Li, P Yang, YL Jiang, Z Lin, YW Pu, LQ Xie… - Biomedicine & …, 2020 - Elsevier
… to the anti-apoptotic protein Bcl-2. I/R injury had resulted in up-regulation of Bax and cleaved-…
function was effectively protected and the damage of ischemic myocardium was repaired. …
function was effectively protected and the damage of ischemic myocardium was repaired. …
Egr-1 functions as a master switch regulator of remote ischemic preconditioning-induced cardioprotection
… ischemic preconditioning (RIPC) is a mechanistic process that reduces myocardial infarction
size and protects against ischemia reperfusion (I/R) injury. … ischemia reperfusion (I/R) injury. …
size and protects against ischemia reperfusion (I/R) injury. … ischemia reperfusion (I/R) injury. …
Ginsenoside Rb1 inhibits cardiomyocyte autophagy via PI3K/Akt/mTOR signaling pathway and reduces myocardial ischemia/reperfusion injury
GW Qin, P Lu, L Peng, W Jiang - The American Journal of Chinese …, 2021 - World Scientific
… Ginsenoside Rb1 alleviated rat myocardial injury by inhibiting autophagy through regulation
… In this study, we found that Ginsenoside Rb1 treatment protected myocardial cells against …
… In this study, we found that Ginsenoside Rb1 treatment protected myocardial cells against …
Myocardial ischemia/reperfusion injury: Mechanisms of injury and implications for management
J He, D Liu, L Zhao, D Zhou… - Experimental and …, 2022 - spandidos-publications.com
… our body's innate immunity, protecting against invading pathogens (20). … regulating apoptosis
that is involved in multiple physiological functions and pathological injury, including protein …
that is involved in multiple physiological functions and pathological injury, including protein …
6-Gingerol protects against cardiac remodeling by inhibiting the p38 mitogen-activated protein kinase pathway
S Ma, Z Guo, F Liu, SG Hasan, D Yang… - Acta Pharmacologica …, 2021 - nature.com
… after injury [10, 11]. Therefore, pharmacological inhibition of p38 … in a variety of animal models,
such as rat intestinal ischemia/… or its upstream regulators MKK3/6 can inhibit myofibroblast …
such as rat intestinal ischemia/… or its upstream regulators MKK3/6 can inhibit myofibroblast …