Cardiovascular toxicity related to cancer treatment: a pragmatic approach to the American and European cardio‐oncology guidelines

J Alexandre, J Cautela, S Ederhy… - … of the American …, 2020 - Am Heart Assoc
… most up‐to‐date version of each guideline and data from recent studies. These protocols
provide practical easy‐to‐use algorithms to help clinicians make daily decisions. In therapeutic …

Toxigen: A large-scale machine-generated dataset for adversarial and implicit hate speech detection

T Hartvigsen, S Gabriel, H Palangi, M Sap… - arXiv preprint arXiv …, 2022 - arxiv.org
… that finetuning a toxicity classifier on our data improves its … In the first approach, we are also
able to detoxify model … and well-informed policy & regulation in bringing scalable and reliable …

Trial designs using real‐world data: the changing landscape of the regulatory approval process

E Baumfeld Andre, R Reynolds… - … and drug safety, 2020 - Wiley Online Library
… ) (Started 2015)33 This project aims to facilitate the establishment and systematic approach
to use of patient registries in order to collect high-quality data for regulatory decision-making. …

Nanomaterials in the Environment Acquire an “Eco‐Corona” Impacting their Toxicity to Daphnia Magna—a Call for Updating Toxicity Testing Policies

F Nasser, J Constantinou, I Lynch - Proteomics, 2020 - Wiley Online Library
… with, and thus any toxicity data obtained would be reflective of … Here, we aim to bring a new
perspective on the importance … and is therefore used as a population regulatory mechanism. …

MicroRNA-mediated inhibition of transgene expression reduces dorsal root ganglion toxicity by AAV vectors in primates

J Hordeaux, EL Buza, B Jeffrey, C Song… - Science translational …, 2020 - science.org
… and develop an approach to eliminate DRG toxicity, we … data in data file S1) and DRG-related
toxicity (raw data in … concerns raised by regulatory agencies for DRG toxicity, we believe …

Targeting cancer cells with nanotherapeutics and nanodiagnostics: Current status and future perspectives

ES Ali, SM Sharker, MT Islam, IN Khan, S Shaw… - Seminars in cancer …, 2021 - Elsevier
… –100 nm) used in the design, fabrication, regulation, and application of therapeutic drugs or
… no toxicity concerns. Similarly, diagnostic imaging holds promising future applications with …

Per and poly-fluoroalkyl substances (PFAS) as a contaminant of emerging concern in surface water: A transboundary review of their occurrences and toxicity effects

A Podder, AHMA Sadmani, D Reinhart… - Journal of hazardous …, 2021 - Elsevier
Use of long-chain PFAS decreased due to regulations … From the data analysis in this study,
occurrences of PFOA and … and consequential toxicological effects from a global perspective. …

Global burden of disease due to smokeless tobacco consumption in adults: an updated analysis of data from 127 countries

K Siddiqi, S Husain, A Vidyasagaran, A Readshaw… - BMC medicine, 2020 - Springer
… We used a novel approach, whereby we classified ST … toxicity of ST products and the role
of both formal and informal sectors in its production, distribution and sale make ST regulation a …

Exposure pathways, levels and toxicity of polybrominated diphenyl ethers in humans: A review

Z Wu, C He, W Han, J Song, H Li, Y Zhang, X Jing… - Environmental …, 2020 - Elsevier
… common use of PBDEs, their levels in humans from the USA were … Human toxicity data
demonstrated that PBDEs have … , including diverse regulations and the usage of PBDE technical …

Environmental life cycle assessment of battery electric vehicles from the current and future energy mix perspective

M Shafique, X Luo - Journal of Environmental Management, 2022 - Elsevier
… battery data from the Greenhouse Gases, Regulated … study used the ecointvent/ELCD,
USLCI and Industry data 2.0 … analysis)), USA (to represent EV production in USA and Canada), …