… Subsequent studies confirmed the consistent involvement of chromosomes 9 and 22, … :
Removal ofpoly(A) and consequent degradation of c-fos mRNA facilitated by 3' AUrich sequences…

… Although the basic tenets of the molecular mechanisms by which the DNA sequence is
transcribed into the mRNA, which in turn is translated into the proteins remain unchallenged, the …

… ride (LPS), an effect abolished by removal of AU-rich motifs within the 3′-UTR. The … Removal
of poly(A) and consequent degradation of c-fos mRNA facilitated by 3′ AU-rich sequences…

… In mouse T cells the deletion of m6A ‘writer’ protein METTL3 … roles for inducible degradation
of SOCS mRNAs in response … through AU-rich elements in the 3′ UTR of PD-L1 mRNA. …

… ΔFosB mRNA is generated by the removal of intron 4 (also … As a consequence, ΔFosB lacks
degradation signals present … could be observed in c-Fos or ΔFosB mRNAs, nor in the levels …

… AU rich elements (AREs) and accelerates the degradation of … was provided by studying the
3-UTR of the c-fos gene64,65. It … Subsequent investigation of deletion mutants of this 3 -UTR …

… and any 3 -bases matching Illumina adaptors were removed. … Because CPA leads to
subsequent downstream termination … been effectively utilized to evaluate protein degradation (48), …

… AU-rich (AREs) or GU-rich elements (GRE) found in the 3’… be alternatively included or removed
from the mature mRNA, and thus … c-fos mRNA, an early response gene whose mRNA is a …

… (generally AAUAAA or an AU-rich sequence), then poly(A) … removed by a decapping enzyme
allowing the mRNA to be … of the c-fos promoter. This mechanism allows different levels of …

… -transcriptional regulation either by degradation of the target … The 3′UTRs also facilitate
post-transcriptional regulation … ) to remove those consisting of low-complexity sequences. An …