Cold shock domain–containing protein E1 is a posttranscriptional regulator of the LDL receptor

GA Smith, A Padmanabhan, BH Lau… - Science translational …, 2022 - science.org
3′UTR of its ortholog ldlra (XM_005163870.4) is AU rich … effects on other transcripts, such
as c-Fos (58). We have also … a human variant with a large deletion in the LDLR 3′UTR, the …

Oncolytic Adenovirus Utilizing RNA Stabilization Mechanism Can Synergize with Chemotherapy

E HOSSAIN - 2020 - eprints.lib.hokudai.ac.jp
… Oncolytic adenovirus can be engineered by the deletion of … for rapid degradation of mRNA
and the fate of AREmRNA is … c-fos AU-rich elements (ARE) in the 3'-untranslated region (3'-…

ELAV-Mediated mRNA Transport in Memory Formation

AA Mirisis - 2023 - search.proquest.com
… of the defensive tail-elicited siphon withdrawal reflex (T-SWR) … c-Jun can associate with the
transcription factor, c-Fos, to form … AU-rich elements (AREs) are found in the 3' UTR of many …

MicroRNA-Mediated Migration of Colon Cancer Cells

A Algaber - 2021 - portal.research.lu.se
… details, and we will remove access to the work immediately … -5p at AU rich element region
in 3ʹ-UTR of HuR mRNA. In … , including those that can be found in c-fos mRNA. (ii) Class II …

Emerging roles of RNA-binding proteins in neurodevelopment

AS Parra, CA Johnston - Journal of Developmental Biology, 2022 - mdpi.com
… zipcodes [34] that facilitate formation of a transport complex … -8 to recruit RISC to degrade
Yki mRNA. A similar mechanism … in mice and a double deletion of LIN28A/B leads to neural …

[HTML][HTML] Crystallin gene expression: Insights from studies of transcriptional bursting

A Cvekl, C Eliscovich - Experimental eye research, 2021 - Elsevier
… The mRNA degradation processes are triggered by … In contrast to the removal of nuclei in
mammalian erythrocytes via … remained coated by a number of RBPs that facilitates their nuclear …

Local transport and translation of BDNF following synaptic potentiation

G Bimbi - 2023 - arts.units.it
… BDNF mRNAs to dendrites for local translation would facilitate … , the Tet-off blocking is removed
and the expression of the … spread of mRNAs recruited, and the subsequent proteins newly …

The archer and the prey: the duality of PAF1C in antiviral immunity

MW Kenaston, PS Shah - Viruses, 2023 - mdpi.com
… However, the disruption of PAF1C by removing individual … One novel interacting partner,
AU-rich RNA-binding and … mitochondria, leading to protein degradation via mitophagy. The …

Hu antigen R (HuR) protein structure, function and regulation in hepatobiliary tumors

S Lachiondo-Ortega, TC Delgado, B Baños-Jaime… - Cancers, 2022 - mdpi.com
… RRMs to AU-rich elements (AREs), typically present in the 3′-… , thus, preventing mRNA
degradation and deadenylation. To … Moreover, deletion of RRM3 critically impaired the ability of …

Kaposi's sarcoma-associated herpesvirus modulates the unfolded protein response during lytic replication

BP Johnston - 2020 - dalspace.library.dal.ca
… by viral gene products may effectively remove an anti-viral host … other bZIP transcription
factors including c-fos and ATF6, … and subsequent proteasomal degradation of FOXO1, which …