Kaposi's sarcoma-associated herpesvirus modulates the unfolded protein response during lytic replication

BP Johnston - 2020 - dalspace.library.dal.ca
… by viral gene products may effectively remove an anti-viral host … other bZIP transcription
factors including c-fos and ATF6, … and subsequent proteasomal degradation of FOXO1, which …

[图书][B] The Conserved RNA-Binding Proteins CELF1 and ELAVL1 Mediate Post-Transcriptional Gene Expression Control in Lens Development

S Aryal - 2021 - search.proquest.com
… (B) Elavl1 gene deletion is confirmed by PCR from Elavl1cKO mouse lens genomic … the
AU-rich elements (AREs) that support Elavl1 protein binding. (B) RT-qPCR shows Pax6 mRNA is …

[图书][B] Integrin α3β1-Regulated Gene Expression Promotes Cancer Cell Invasion and Metastasis

RP Miskin - 2021 - search.proquest.com
… presence of AU-rich elements (AREs; white bars in the 3’ UTR). … mRNA decay (NSD) and
targeted for degradation by mRNA … pathway for mRNA decay starts with removal of the poly(A) …

Imbalance in cerebral protein homeostasis: Effects on memory consolidation

RA Prado-Alcalá, S González-Salinas… - Behavioural Brain …, 2020 - Elsevier
… by hyperproduction of proteins that lasted three days. We evaluated … mRNA, and they review
literature showing that some genes that are involved in memory consolidation, such as c-fos

The archer and the prey: the duality of PAF1C in antiviral immunity

MW Kenaston, PS Shah - Viruses, 2023 - mdpi.com
… However, the disruption of PAF1C by removing individual … One novel interacting partner,
AU-rich RNA-binding and … mitochondria, leading to protein degradation via mitophagy. The …

The Kinetics of RNA Flow Across Subcellular Compartments

BM Smalec - 2022 - search.proquest.com
degradation, as several pathways that shuttle mRNAs to the nuclear exosome are known to
act on molecules with elongated polyAU-rich elements (AREs) are most commonly found in 3

A SHIFT IN RNA FATE: INVESTIGATING THE ROLE OF C19ORF66 DURING KSHV LYTIC REPLICATION

W Rodriguez Jr - 2023 - scholarworks.umass.edu
… ”, it is removed from the pool of viable mRNAs and will be … a correlation between AU-Rich
elements in each mRNA and its … a cluster of 75 host mRNAs that escape degradation from four …

The Regulation of Human Papillomavirus Type16 Early Gene Expression

X Cui - 2022 - portal.research.lu.se
… details, and we will remove access to the work immediately … by directing it for proteasomal
degradation via the E3 ubiquitin … that regulates mRNA decay by binding AU-rich RNA domains […

Nucleolar R-loops as contributors to Spinal Muscular Atrophy pathophysiology

N Berrueta Ramirez - 2023 - etheses.whiterose.ac.uk
… (SMN) protein, due to deletion or mutation of SMN1 gene. … resolve topological issues and
facilitate transcription; however, … , all three subunits are necessary for the degradation of RNA. …

Dance with the devil: stress granules and signaling in antiviral responses

N Eiermann, K Haneke, Z Sun, G Stoecklin, A Ruggieri - Viruses, 2020 - mdpi.com
AU-rich elements (AREs) located in the 3′ UTR of many cytokine and IFN mRNAs, prevents
rapid degradation of these mRNAs … While uORFs facilitate translation of mRNAs under such …