[HTML][HTML] Loss of heterozygosity and its importance in evolution

CS Heil - Journal of molecular evolution, 2023 - ncbi.nlm.nih.gov
… at a rate higher than the point mutation rate, and can impact … has identified and linked
changes in ploidy, copy number … there are more than two heterozygous haplotypes, which can …

Impact of inter-species hybridisation on antifungal drug response in the Saccharomyces genus.

F Visinoni, W Royle, R Scholey, Y Hu, S Timouma… - bioRxiv, 2024 - biorxiv.org
… A library of Saccharomyces cerevisiae x S. kudriavzevii hybrid … by the accumulation of point
mutations which alter the structure … no significant difference in growth across both conditions (…

Mapping mitonuclear epistasis using a novel recombinant yeast population

THM Nguyen, A Tinz-Burdick, M Lenhardt… - PLoS …, 2023 - journals.plos.org
… intercrossed population of Saccharomyces cerevisiae yeasts, … activities and mtDNA copy
number differences, prompting … showed MIP1 haplotype x mitonuclear haplotype effects. …

Antifungal susceptibility of clinical yeast isolates from a large Canadian reference laboratory and application of whole-genome sequence analysis to elucidate …

LR McTaggart, A Cabrera, K Cronin… - Antimicrobial Agents …, 2020 - Am Soc Microbiol
Comparison of genome-wide copy number variation between … albicans (55), and point
mutations and increased expression of … albicans SC5314 haplotype A version A22, C. glabrata …

Application of Novel Short Tandem Repeat Typing for Wickerhamomyces anomalus Reveals Simultaneous Outbreaks within a Single Hospital

B Spruijtenburg, SM Rudramurthy, EFJ Meijer… - Microorganisms, 2023 - mdpi.com
… based on a Saccharomyces cerevisiae CYP51 template with … via single point mutations, is
only seven in comparison to the … related with a single copy number difference in marker M3-a. …

Aneuploidy and gene dosage regulate filamentation and host colonization by Candida albicans

P Kakade, S Sircaik, C Maufrais… - Proceedings of the …, 2023 - National Acad Sciences
… Studies on the model yeast Saccharomyces cerevisiae … work, we show that acquisition of an
extra copy of Chr 7 in C. … Reads were aligned to the SC5314 reference genome (haplotype A …

Strain background of Candida albicans interacts with SIR2 to alter phenotypic switching

AL Woodruff, J Berman, M Anderson - Microbiology, 2024 - microbiologyresearch.org
… (LOH), copy number variations (CNVs) and point mutations that can … elegans or Saccharomyces
cerevisiae found different … Δ/Δ mutants is a trisomic Chr6 with an ABB haplotype. High-…

[HTML][HTML] Use of a Candida albicans SC5314 PacBio HiFi reads dataset to close gaps in the reference genome assembly, reveal a subtelomeric gene family, and …

LL Hoyer, BA Freeman, EK Hogan… - Frontiers in Cellular …, 2024 - ncbi.nlm.nih.gov
… of a Saccharomyces cerevisiae strain S288C size standard. … them onto a specific chromosome
haplotype. The PacBio HiFi … was attributable to differences in tandem repeat copy number. …

[PDF][PDF] Mitotic recombination between homologous chromosomes drives genomic diversity in diatoms

…, M Sekulić, D Jallet, C Nef, C Van Oosterhout… - Current Biology, 2021 - cell.com
… of recombined haplotypes, loss of heterozygosity, and copy … We sought to detect LOH and
copy number variation (CNV) … the number of beneficial single-point mutations, but rather by …

Identifying targets of selection in laboratory evolution experiments

AA Martínez, GI Lang - Journal of Molecular Evolution, 2023 - Springer
… For example, we directly compared adaptation at two … , the yeast Saccharomyces cerevisiae
has two mating types and can … Like point mutations, copy number variations (CNVs) can also …