… for those at highest risk who were offered 5-yearly colonoscopy from … MISCAN-Colon is a
well-established microsimulation model for … points and adjusted the participation of rescreening. …

… that asymptomatic individuals with a positive mtsDNA test and a negative high-quality … In
another modeling study, rescreening 10 years after a negative screening colonoscopy at age 50 …

… The semi-Markov microsimulation model simulated the effect of screening and other … The
model evaluated five rescreening strategies for individuals with a negative colonoscopy result …

… suggested PCCRC was a result of missed CRN in more than … Because colonoscopy is not
conducted on those with a negative … Before mt-sDNA availability, microsimulation adjusting for …

… often need to be rescreened at regular intervals to maintain the … suggesting that FIT and
colonoscopy reduce the incidence of … and harms of screening from microsimulation modeling. …

… Individuals aged 50–74 – who had not had a colonoscopy in … -users among those who
agreed with all negative emotional … getting an abnormal result” variable (Supplementary table 2). …

… have been justified by microsimulation models (9) but most … We define a new probability for
the rescreening “window of … on rescreen were very close to those found for rescreening both …

… However, persistence or regular rescreening for those with negative results should also be
… include standardized measures of completion of colonoscopy in those with a positive result. …

… test method(s), the location, and the number of rescreening … study sample micro-simulation
models, in which individuals lives … , rural regions—could result in lower participation rates for …

… evaluated using MISCAN microsimulation modeling and cost-… In one study, individuals who
screened negative prior to 2009 … In part, this may result from concerns about implementation …