Folate supplementation during oocyte maturation positively impacts the folate-methionine metabolism in pre-implantation embryos

S Saini, V Sharma, S Ansari, A Kumar, A Thakur… - Theriogenology, 2022 - Elsevier
… pre-implantation embryo development in response to change … is present in bovine oocytes
and pre-implantation embryos, … in oocyte maturation medium and embryo culture medium? (ii…

… S-Adenosyl-l-Homocysteine Affect the Expression of Genes Related to the Epigenetic Machinery and Change the DNA Methylation Status of In Vitro Cultured Bovine …

NAB Schumann, AS Mendonça, MM Silveira… - DNA and Cell …, 2020 - liebertpub.com
… of procaine and SAH during bovine cell culture was able to alter … Reactions were optimized
to provide a maximum amplification … Studies with bovine embryos have shown that the TET1 …

Interspecific variation in one-carbon metabolism within the ovarian follicle, oocyte, and preimplantation embryo: consequences for epigenetic programming of DNA …

CE Clare, V Pestinger, WY Kwong, DAR Tutt… - International Journal of …, 2021 - mdpi.com
… in response to 1C substrate (eg, methionine) or cofactor … methionine (from 50 to 10 µM) during
bovine embryo culture leads … TALP media supplemented with 10 or 50 μM methionine and …

Metabolism-epigenetic interactions on in vitro produced embryos

MP Milazzotto, J Ispada… - Reproduction, Fertility and …, 2022 - CSIRO Publishing
… Thus, the metabolic changes induced by the response to the … METTL3 acts as a binding
subunit for the S-adenosyl methionine (… In bovine embryos, the presence of methionine in culture

Amino acids and the early mammalian embryo: Origin, fate, function and life-long legacy

HJ Leese, PJ McKeegan, RG Sturmey - International Journal of …, 2021 - mdpi.com
… 2A, which converts methionine to s-adenosyl methionine, is … a culture medium deficient in
methionine prevented embryos from … Adaptive responses by mouse early embryos to maternal …

An overview of reactive oxygen species damage occurring during in vitro bovine oocyte and embryo development and the efficacy of antioxidant use to limit these …

JA Keane, AD Ealy - Animals, 2024 - mdpi.com
… occurs because ROS target S-adenosyl methionine (SAM), a … production, and this
dehydrogenase reaction requires H 2 O … whether Zn supplementation is useful in different IVC …

Epigenetic remodeling of chromatin in human ART: Addressing deficiencies in culture media

Y Ménézo, K Elder - Journal of assisted reproduction and genetics, 2020 - Springer
… Human oocytes/early embryos are readily able to incorporate methionine efficiently from
the … of SAM (S-adenosyl methionine) and downstream methylation reactions involved with …

[HTML][HTML] Effects of choline on the phenotype of the cultured bovine preimplantation embryo

E Estrada-Cortés, VM Negrón-Peréz, P Tríbulo… - Journal of dairy …, 2020 - Elsevier
… In conclusion, addition of choline to the culture medium … whether culture medium affects
embryonic response to choline. … in choline metabolism during early embryonic development but …

One-carbon metabolite supplementation to heifers for the first 14 d of the estrous cycle alters the plasma and hepatic one-carbon metabolite pool and methionine …

MS Crouse, HC Freetly… - Journal of Animal …, 2023 - academic.oup.com
… role in the responses to methionine supplementation. Furthermore, there are multiple …
effects between in vitro culture of an immortalized cell line of bovine embryonic fibroblasts and in …

Metabolic enhancement of the one carbon metabolism (OCM) in bovine oocytes IVM increases the blastocyst rate: evidences for a OCM checkpoint

A Golestanfar, A Niasari-Naslaji, F Jafarpour… - Scientific Reports, 2022 - nature.com
Methionine is converted to S-adenosyl methionine (SAM) … The balance of these
reactions and the partitioning of … might occur supplementing also the embryo culture in vitro …