Reverse vaccinology and its applications

AM Kanampalliwar - Immunoinformatics, 2020 - Springer
… based on the application of vaccinomics science to vaccinology. The first example of such
an approach is reverse vaccinology. Reverse vaccinology reduces the period of vaccine target …

Vaccine types and reverse vaccinology

AN Oli, AB Rowaiye - Vaccinology and methods in vaccine research, 2022 - Elsevier
Vaccinology is a relatively recent discipline involving vaccine development and use. It includes
immunology and infectious illnesses, epidemiology, public health, and pediatrics among …

A guide to current methodology and usage of reverse vaccinology towards in silico vaccine discovery

SJ Goodswen, PJ Kennedy… - FEMS Microbiology …, 2023 - academic.oup.com
… Reasons why reverse vaccinology is now a reality. The emergence of reverse vaccinology is
… Bioinformatics is the glue that binds these four forces to make reverse vaccinology a reality. …

The promising potential of reverse vaccinology-based next-generation vaccine development over conventional vaccines against antibiotic-resistant bacteria

K Khalid, CL Poh - Vaccines, 2023 - mdpi.com
… in silico immunoinformatics techniques and reverse vaccinology. The bioinformatics approach
can … vaccine development based on the reverse vaccinology approach and highlights the …

Reverse engineering protection: A comprehensive survey of reverse vaccinology-based vaccines targeting viral pathogens

S Ponne, R Kumar, SM Vanmathi, RSN Brilhante… - Vaccine, 2024 - Elsevier
… Introduction to reverse vaccinology The reverse vaccinology (RV) approach can be traced
back to 2000 when Rino Rappuoli first introduced the term “RV” [1]. In his review, he has …

Reverse vaccinology approach to design a novel multi-epitope vaccine candidate against COVID-19: an in silico study

M Enayatkhani, M Hasaniazad, S Faezi… - Journal of …, 2021 - Taylor & Francis
Reverse vaccinology approach to design a .... … In this study, we designed a suitable vaccine
candidate against COVID-19, by exploiting the programs of reverse vaccinology ( Figure 1 ) …

Designing a Next-Generation Multiepitope-Based Vaccine against Staphylococcus aureus Using Reverse Vaccinology Approaches

SR Mahapatra, J Dey, TK Raj, N Misra, M Suar - Pathogens, 2023 - mdpi.com
Staphylococcus aureus is a human bacterial pathogen that can cause a wide range of
symptoms. As virulent and multi-drug-resistant strains of S. aureus have evolved, invasive S. …

Vaxign2: the second generation of the first Web-based vaccine design program using reverse vaccinology and machine learning

E Ong, MF Cooke, A Huffman, Z Xiang… - Nucleic acids …, 2021 - academic.oup.com
Vaccination is one of the most significant inventions in medicine. Reverse vaccinology (RV)
is a state-of-the-art technique to predict vaccine candidates from pathogen's genome(s). To …

In silico analysis of epitope-based vaccine candidate against tuberculosis using reverse vaccinology

S Bibi, I Ullah, B Zhu, M Adnan, R Liaqat, WB Kong… - Scientific reports, 2021 - nature.com
… This study aimed to develop a TB epitope ensemble vaccine for new access in reverse
vaccinology. The method has recently started to be demonstrated by the discovery of the epitope …

Identification of vaccine and drug targets in Shigella dysenteriae sd197 using reverse vaccinology approach

K Jalal, T Abu-Izneid, K Khan, M Abbas, A Hayat… - Scientific reports, 2022 - nature.com
… Therefore, in the current study, a Reverse Vaccinology approach was adapted to identify
unique vaccine candidates and design the novel vaccine construct against the Sd197 strain of …