… this review is ILCs. ILC1s are dependent on the T-box transcription factor T-bet and produce
interferon gamma (… a more persistent effect than is endowed by trained immunity 81,94,95 . …

… to improve the safety and effectiveness of cytokine immunotherapy. In this review we
highlight recent advances in cytokine biology and engineering for cancer immunotherapy. …

… of IFN production is crucial because chronic IFN responses can have deleterious effects on
both … Here, we review the antitumor effect of IFN-γ by dividing it into three main mechanisms, …

… effects as monotherapy or combination therapy for both preclinical and clinical applications
will be discussed in this review. … + T cells while impairing cytokine production from NK cells in …

… ) or of increased type I interferon production and signalling in … or immune interferon) is a
cytokine with multiple effects on … of T cell-engaging immunotherapeutic agents (such as chimeric …

… This review assessed IFNγR polymorphisms, expression and … are insensitive to the
antiproliferative effects of the IFN-γ/STAT1 … of the IFNγR signaling suppressed production of IFN-γ …

… available recombinant human IFN-γ used … human PBMCs, IFN-γ treatment does not directly
induce p40 gene expression and protein production, but it primes monocytic cells to produce …

… In this review, we describe the crucial role of γδ T cells in anti-… like profile, with a characteristic
production of IFN-γ and TNF-… : Implications for the development of adoptive immunotherapy …

… immunotherapy for different types of cancer. Moreover, it … IFN-γ-dependent pro- and
anti-tumorigenic effects. This … In summary, IFN-γ is produced in response to numerous stimulants …

… This review will highlight the recent advancements of gamma-… the safety and tolerability of
recombinant human IL-15 (rhIL-15, … this review, but could have important implications in cancer …