Nanotechnology based delivery systems of drugs currently used to treat alzheimer's disease

N Choubdar, S Avizheh - Nanoscience & Nanotechnology-Asia, 2020 - ingentaconnect.com
PLGA and poly buty1 cyanoacrylate (PBCA) carriers for sustained brain delivery. RT loaded
PLGA and PBCA were prepared … a statistical analysis performed under optimized predicted …

Targeting the central nervous system: From synthetic nanoparticles to extracellular vesicles—Focus on Alzheimer's and Parkinson's disease

S Hernando, E Santos‐Vizcaíno… - Wiley …, 2023 - Wiley Online Library
… biological NPs with numerous characteristics that qualify them as … , current therapies are far
from optimal; treating the symp… et al. prepared PLGA and poly (butylcynanoacrylate) (PBCA) …

Recent advances in nanotherapeutic interventions for the treatment of Alzheimer's disease

A Dogra, RS Narang, JK Narang - Current Pharmaceutical …, 2020 - ingentaconnect.com
… significantly enhanced 125I-CQPBCA NPs retention in the mice … Preparation, characterization,
in vivo biodistribution and … evaluation of rivastigmine loaded chitosan nanoparticles for …

[PDF][PDF] Nanodelivery systems for Alzheimer's disease: Prospects of natural therapeutic agents

OA Odeku, TO Ajala - Journal of Applied Pharmaceutical Science, 2021 - japsonline.com
… ; the rivastigmine-loaded nanoparticles were administered to mice with scopolamine-induced
amnesia. The results showed that mice given rivastigmine-loaded nanoparticles showed a …

In situ encapsulation of rivastigmine in TAT-functionalized P (MMA-co-AA) nanoparticles through miniemulsion polymerization

LHR Mangia, HC Ferraz, RSD Souza… - Colloids and Surfaces A …, 2021 - Elsevier
… and use of nanocarriers for optimization of drug delivery, … to characterize the cytotoxicity of
obtained nanoparticles, which … of the toxicity of rivastigmine-loaded nanoparticles and their …

Biodegradable polymeric nanoparticles for brain-targeted drug delivery

K Kempe, JA Nicolazzo - Nanomedicines for brain drug delivery, 2021 - Springer
… This chapter will provide an up-to-date account on the various polymeric nanoparticle approaches
… techniques that can be employed for the preparation of these polymeric nanoparticles. …

PLGA mediated drug delivery for Alzheimer's disease

T Pandya, M Kulkarni, S Acharya… - Alzheimer's Disease and …, 2024 - Elsevier
… , to reach the brain in optimal concentrations. A strategy incorporating surface functionalized
… about methylene blue nanoparticles, preparation, and characterization, for treatment of AD …

[PDF][PDF] Optimization and characterization of rivastigmine-loaded nanostructured lipid carriers

S Ganna, SM Kotakadi, RA Mohammed… - Int. J. Curr. Pharm …, 2021 - academia.edu
… Considering these, in the present study, we developed rivastigmine loaded novel NLCs
using appropriate concentrations of fish and flaxseed oil by melting emulsification coupled with …

Polysorbate-coated mesoporous silica nanoparticles as an efficient carrier for improved rivastigmine brain delivery

SF Basharzad, M Hamidi, A Maleki, Z Karami… - Brain Research, 2022 - Elsevier
… Herein, we report a facile strategy to prepare highly … Our developed PS-coated NPs
characterized through … –desorption analysis, and Fourier transform infrared (FT-IR) analysis. The …

[HTML][HTML] Double optimization of rivastigmine-loaded nanostructured lipid carriers (NLC) for nose-to-brain delivery using the quality by design (QbD) approach …

S Cunha, CP Costa, JA Loureiro, J Alves, AF Peixoto… - Pharmaceutics, 2020 - mdpi.com
… In this work, we performed a double optimization of a rivastigmine-loaded NLC formulation
… used to prepare NLC formulations (Table 1) and the best ratio was selected after analysis of …