Optimized rivastigmine nanoparticles coated with eudragit for intranasal application to brain delivery: evaluation and nasal ciliotoxicity studies

M Bhanderi, J Shah, B Gorain, AB Nair, S Jacob… - Materials, 2021 - mdpi.com
… to develop mucoadhesive rivastigmine loaded in chitosan and … were optimized to obtain
chitosan nanoparticles having the … This analysis was performed to evaluate the mucoadhesive …

Applications of Nanotechnology in Alzheimer's Disease

P Vlamos, IS Kotsireas, I Tarnanas - 2022 - helios-eie.ekt.gr
PLGA-b-PEG diblock copolymer-based nanoparticles were loaded with the diabetes drug
… The inherent hydrophobic and electrostatic characteristics of nanoparticles are widely …

Bioinspired lipid-polysaccharide modified hybrid nanoparticles as a brain-targeted highly loaded carrier for a hydrophilic drug

SH Omar, R Osman, W Mamdouh… - International Journal of …, 2020 - Elsevier
… the characteristics of DxC surface modified and unmodified lipid/PLGA hybrid NPs prepared
… Hence, the optimization in this work focused on the control of the supersaturation level. A …

Potential of nanoparticles as novel therapeutics against Alzheimer's disease

RR Ujjwal, SK Maharana, M Handa… - … Drug Delivery for …, 2022 - Elsevier
… methods demonstrate that they need further optimization prior to human use. … PBCA
curcumin NPs (ApoE3-CPBCA) for enhancing cellular uptake as well as photostability. Prepared

Organic nanocarriers for brain drug delivery

M Lúcio, CM Lopes, E Fernandes… - Nanoparticles for …, 2021 - taylorfrancis.com
… used for NC administration, providing an analysis of the advantages and disadvantages of
each … NC surface modification appears to be a key strategy to optimise drug delivery by the in …

[PDF][PDF] Nanotechnology-based drug delivery systems for treatment of knee injuries and Alzheimer's disease–a review

C Brenckman, S Hossain, NM Ravindra - Material Sci & Eng, 2023 - researchgate.net
… osteoarthritis, with optimal results achieved through the use of liposomes prepared in precise
… Poly(lactic-coglycolic acid) (PLGA) nanoparticles loaded with galantamine were created …

Nanotherapeutics for Alzheimer's Disease with Preclinical Evaluation and Clinical Trials: Challenges, Promises and Limitations

SNA Bukhari - Current Drug Delivery, 2022 - ingentaconnect.com
… In addition, the possibility to optimize NP biophysical and biological (ie target-specific …
progressive and irreversible neurodegenerative disorder characterized by memory loss, instability …

[PDF][PDF] Beyond the blood-brain barrier: the use of nanoparticles in drug delivery

C Iga - 2021 - huveta.hu
… loaded PLGA nanoparticles have been prepared with an … rivastigmine than regular rivastigmine
loaded liposomes. The IN … formulation that could deliver optimal doses of nicotinamide to …

Drug delivery systems and strategies to overcome the barriers of brain

Y Garg, DN Kapoor, AK Sharma… - Current Pharmaceutical …, 2022 - ingentaconnect.com
… It is characterized by cerebral microvascular endothelial tight … nanoparticles’; ‘Brain + PLGA
nanoparticles’; ‘Brain + PBCAPBCA based NPs can be prepared by either polymerization …

Therapeutic nanoparticles and their targeted delivery applications

AA Yetisgin, S Cetinel, M Zuvin, A Kosar, O Kutlu - Molecules, 2020 - mdpi.com
… of nanoparticles in the biological systems. We emphasize on the type of clinically used
nanoparticles … Understanding of the characteristics of nanoparticles and their interactions with the …