… Insights from this case study that have led to the synthesis of the novel allopurinol derivative
were discovered by visual analysis of the output frames of the MD runs of the allopurinol and …

Candidate drugs targeting the central nervous system (CNS) demonstrate extremely low
clinical success rates, with more than 98% of potential treatments being discontinued due to …

… of PBCA nanoparticles coated with polysorbate-80. However, that approach is not optimal
… Some groups developed rivastigmine-loaded chitosan nanoparticles using the ionotropic …

… In other words, preparing particles with desirable characteristics using this … prepare a system
with the possibility of actual use, cell compatibility and antibacterial properties of the optimal …

… Rivastigmine-loaded PLGA and PBCA nanoparticles: preparation, optimization,
characterization, in vitro and pharmacodynamic studies. European journal of pharmaceutics and …

… DoE, optimization and multivariate data analysis is … nanoparticles yield, %EE and particle
size using BBD to obtain the controlled release of linamarin from optimized PLGA nanoparticles…

… This finding was previously demonstrated for rivastigmine-loaded PLGA nanoparticles,
where the copolymer concentration was the major factor affecting the drug EE%. Citation53 It …

… Formulation and optimization of coated PLGA - Zidovudine nanoparticles using factorial
design and in vitro in vivo evaluations to determine brain targeting efficiency. Saudi Pharm J. …

… study aims to prepare, characterize, and evaluate PCL nanoparticles (PCL … Cytarabine
loaded PCL NPs were prepared via the nano-… Such nanoparticle size is optimal for intravenous …

… , while PBCA nanoparticles (as the core of the nanocarrier) were prepared using the
emulsion polymerization method. The characteristics of UA-BSA-coated PBCA nanocomplexes …