Translational Challenges

B Rocha, NP Rocha, B Gago - Nanoparticles for Brain Drug …, 2021 - taylorfrancis.com
… , nanoparticles emerge as a powerful and promising strategy for disease prevention and
management by delivering drugs in the optimal dose … , for instance, the characterisation of early …

Fe3O4@ SiO2@ CeO2 as a potential nanomagnetic carrier for oral delivery system and release of celecoxib

S Ahmadvand, MK Razi, B Sadeghi… - … Chemistry & High …, 2022 - ingentaconnect.com
… was made to synthesize, characterize, and develop many … , HA nanoparticles/polymeric poly
lactide-co-glycolide (PLGA) … In this experiment, our goal is to find the optimal concentration …

Polymeric Nanoparticles that Entrap Drug Combinations Targeted to Solid Tumors

S Dilip Kumar, M Aashabharathi, S Aradhana… - Polymeric nanoparticles …, 2022 - Springer
… Recent efforts in improving the efficiency of nanoparticle synthesis and exploring their
biomedical applications will hopefully lead to the implementation of these approaches on a large …

Transferosome: A Transdermal Vesicular Drug Delivery for the Treatment of Skin Cancer

H Gayathri, S Sangeetha - Annals of the Romanian Society for Cell …, 2021 - annalsofrscb.ro
… In this review, the detailed study of the transferosomes loaded topical preparations with
anticancer drugs like 5fluorouracil,cisplatin etc and to characterize the parameters like drug …

Lipid-core nanocapsules containing simvastatin improve the cognitive impairment induced by obesity and hypercholesterolemia in adult rats

R Lorenzoni, S Davies, LM Cordenonsi… - European Journal of …, 2020 - Elsevier
… This study aimed to develop and characterize lipid-core nanocapsules (LNC) containing SV
(SV-LNC) or LV (LV-LNC), evaluating the effects of SV-LNC in an animal model of cognitive …

[HTML][HTML] Lung cancer targeting efficiency of Silibinin loaded Poly Caprolactone /Pluronic F68 Inhalable nanoparticles: In vitro and In vivo study

P Patel, M Raval, A Manvar, V Airao, V Bhatt, P Shah - PLoS One, 2022 - journals.plos.org
… Design-Expert software was used to perform various RSM computations for the current
optimization analysis (version 11.0.0.0). Using a multiple linear regression analysis technique, a …

Preparation and In vitro release of Isoniazid and Rifampicin loaded nanoparticles

M Targhotra, MK Chauhan - Nanomedicine Journal, 2024 - nmj.mums.ac.ir
… Materials and Methods: Box-Behnken Design (BBD) was used for optimizing the
nanoparticles. Eudragit was used in the preparations in varying concentrations (1-2% w/v). The …

[HTML][HTML] Fluorinated molecules and nanotechnology: future 'avengers' against the Alzheimer's disease?

M Dabur, JA Loureiro, MC Pereira - International journal of molecular …, 2020 - mdpi.com
… Therefore, we suggest a combination of nanotechnology with fluorinated molecules can
be a promising/potential therapeutic treatment to meet the desired pharmacokinetic/…

[HTML][HTML] Passing of Nanocarriers across the Histohematic Barriers: Current Approaches for Tumor Theranostics

K Gareev, R Tagaeva, D Bobkov, N Yudintceva… - Nanomaterials, 2023 - mdpi.com
… Herein, we have described the main characteristics and methods of the application of … of
PLGA synergistically increased nanoparticle uptake by glioblastoma cells (Table 2). The optimal

[HTML][HTML] Brain delivery of nanomedicines: trojan horse liposomes for plasmid DNA gene therapy of the brain

WM Pardridge - Frontiers in Medical Technology, 2020 - frontiersin.org
Non-viral gene therapy of the brain is enabled by the development of plasmid DNA brain
delivery technology, which requires the engineering and manufacturing of nanomedicines that …