Cannabis-drug interactions: Implications for medicinal cannabis use

FM Gengo, AG Mattle, CC Ralyea Jr - Medicinal Usage of Cannabis and …, 2023 - Elsevier
… CBD can either inhibit or compete for various cytochrome P450 (CYP) … predict moderate to
strong inhibition by Δ9THC for CYP: … Similarly, a study was conducted in 15 healthy subjects to …

Mass Spectrometric Methods for Evaluation of Voriconazole Avian Pharmacokinetics and the Inhibition of its Cytochrome P450-induced Metabolism

AF Lehner, SD Johnson, L Dirikolu… - Toxicology …, 2024 - Taylor & Francis
… by CYP1A2 in manners similar to tizanidine, for example. Schulz, … is a powerful demethylase
for caffeine, and in humans, … CYP targets of the inhibitors studied during this research. Bold …

Neuroprotective effects of coffee bioactive compounds: a review

K Socała, A Szopa, A Serefko, E Poleszak… - International journal of …, 2020 - mdpi.com
… Several cytochrome P450 (CYP) isoforms are implicated in caffeine … 74 patients with
Alzheimer’s disease and 72 healthy subjects … This study showed that caffeine intake was inversely …

Synthesis, molecular docking, and biological evaluation of 5‐alkyl (aryl)‐2‐isobutylthiazole derivatives: As α‐amylase, α‐glucosidase, and protein kinase inhibitors

S Khan, N Buğday, AU Rehman, IU Haq… - Applied …, 2022 - Wiley Online Library
… The study of enzyme inhibition is still a popular topic in … total cytochrome P450 (CYP)
concentration in the liver. Phenacetin, tizanidine, theophylline, clozapine, zolmitriptan, and caffeine