[HTML][HTML] WNT/β-catenin signaling in hepatocellular carcinoma: The aberrant activation, pathogenic roles, and therapeutic opportunities
A Gajos-Michniewicz, M Czyz - Genes & Diseases, 2024 - Elsevier
… understanding of how WNT/β-catenin signaling facilitates the HCC development, acquisition
… lead to activated WNT/β-catenin signaling in HCC. We discuss the pivotal roles of CTNNB1 …
… lead to activated WNT/β-catenin signaling in HCC. We discuss the pivotal roles of CTNNB1 …
Clinical significance of the duality of Wnt/β-catenin signaling in human hepatocellular carcinoma
T Aoki, N Nishida, M Kudo - Cancers, 2022 - mdpi.com
… HCC with activated Wnt/β-catenin signaling pathway. It could be … Wnt/β-catenin signaling
pathway should be detected non-invasively and applied to the treatment of advanced HCC…
pathway should be detected non-invasively and applied to the treatment of advanced HCC…
β-Catenin signaling in hepatocellular carcinoma
C Xu, Z Xu, Y Zhang, M Evert… - … Journal of clinical …, 2022 - Am Soc Clin Investig
… and oncogenic roles of aberrant Wnt/β-catenin signaling during hepatocarcinogenesis. In …
of how the Wnt/β-catenin pathway contributes to HCC molecular pathogenesis remains …
of how the Wnt/β-catenin pathway contributes to HCC molecular pathogenesis remains …
Wnt/β-catenin signaling as a driver of hepatocellular carcinoma progression: an emphasis on molecular pathways
M Deldar Abad Paskeh, S Mirzaei… - … of Hepatocellular …, 2021 - Taylor & Francis
… HCC remains a challenging disease to treat. Wnt/β-catenin signaling pathway is considered
a tumor… present review focused on the role of Wnt signaling in HCC, and its association with …
a tumor… present review focused on the role of Wnt signaling in HCC, and its association with …
Wnt/β-Catenin signaling as a driver of stemness and metabolic reprogramming in hepatocellular carcinoma
RWH Leung, TKW Lee - Cancers, 2022 - mdpi.com
… role in pathogenesis of hepatocellular carcinoma (HCC). In this review, we focus on the
regulatory role of Wnt/β-catenin signaling in cancer … hallmarks of cancer. Understanding the …
regulatory role of Wnt/β-catenin signaling in cancer … hallmarks of cancer. Understanding the …
[HTML][HTML] WNT/β-catenin signaling in the development of liver cancers
S He, S Tang - Biomedicine & pharmacotherapy, 2020 - Elsevier
… of WNT/β-catenin signaling promotes the development and/or progression of liver cancer,
including hepatocellular carcinoma (HCC) … in the development and pathophysiology of liver …
including hepatocellular carcinoma (HCC) … in the development and pathophysiology of liver …
[HTML][HTML] The Wnt/β-catenin signaling pathway in the tumor microenvironment of hepatocellular carcinoma
K Wang, X Qiu, Y Zhao, H Wang… - Cancer Biology & …, 2022 - ncbi.nlm.nih.gov
… roles of the Wnt/β-catenin pathway in the TME of HCC, including its complicated roles in
immune infiltration, cancer stem cell tumor … this pathway is that the Wnt/β-catenin pathway also …
immune infiltration, cancer stem cell tumor … this pathway is that the Wnt/β-catenin pathway also …
β-catenin activation in hepatocellular cancer: implications in biology and therapy
Y Krutsenko, AD Singhi, SP Monga - Cancers, 2021 - mdpi.com
… One major driver of liver cancer is the Wnt–β-catenin pathway which is active in a subset of
these tumors. While this … One common pathway activated in HCC independent of etiology is …
these tumors. While this … One common pathway activated in HCC independent of etiology is …
Dysregulation of Wnt/β‐catenin signaling by protein kinases in hepatocellular carcinoma and its therapeutic application
Q Li, M Sun, M Wang, M Feng, F Yang, L Li… - Cancer …, 2021 - Wiley Online Library
… kinases play essential roles in the pathogenesis of cancer, and kinase … clinical treatment
of cancer. Protein kinases have been reported to regulate the WCS in the pathogenesis of HCC …
of cancer. Protein kinases have been reported to regulate the WCS in the pathogenesis of HCC …
KIF2C: a novel link between Wnt/β-catenin and mTORC1 signaling in the pathogenesis of hepatocellular carcinoma
S Wei, M Dai, C Zhang, K Teng, F Wang, H Li… - Protein & …, 2021 - academic.oup.com
… complex1 (mTORC1) signal transduction. Additionally, we … Wnt/β-catenin pathway, and
acts as a key factor in mediating the crosstalk between Wnt/β-catenin and mTORC1 signaling…
acts as a key factor in mediating the crosstalk between Wnt/β-catenin and mTORC1 signaling…