Calcitonin gene-related peptide (CGRP): role in migraine pathophysiology and therapeutic targeting
… the role of the neuropeptide calcitonin gene-related peptide (… that light-aversive behavior
in mice is migraine-like. This … In addition, rimegepant did not show any effect on liver function, …
in mice is migraine-like. This … In addition, rimegepant did not show any effect on liver function, …
A narrative review of the calcitonin peptide family and associated receptors as migraine targets: Calcitonin gene‐related peptide and beyond
ML Garelja, DL Hay - Headache: The Journal of Head and …, 2022 - Wiley Online Library
… the signaling of calcitonin gene-related peptide (CGRP) are … Light aversive behaviors,
in which rodents spend longer … report that headache is a relatively common side-effect of …
in which rodents spend longer … report that headache is a relatively common side-effect of …
PACAP induces light aversion in mice by an inheritable mechanism independent of CGRP
A Kuburas, BN Mason, B Hing, AS Wattiez… - Journal of …, 2021 - Soc Neuroscience
… (calcitonin gene-related peptide) and PACAP (pituitary adenylate cyclase-activating polypeptide)
in migraine is relevant given that both peptides … that were not light aversive after the first …
in migraine is relevant given that both peptides … that were not light aversive after the first …
Vascular actions of peripheral CGRP in migraine-like photophobia in mice
BN Mason, AS Wattiez, LK Balcziak, A Kuburas… - …, 2020 - journals.sagepub.com
… plays a role in calcitonin gene-related peptide-induced light aversive behavior in mice. … In
addition to light aversion during the initial 30 min period, we also evaluated the effect of VIP on …
addition to light aversion during the initial 30 min period, we also evaluated the effect of VIP on …
Calcitonin gene-related peptide (CGRP) and cluster headache
A Carmine Belin, C Ran, L Edvinsson - Brain sciences, 2020 - mdpi.com
… The neuropeptide calcitonin gene-related peptide (CGRP) is a potent vasodilator produced
… Evidence has accumulated rapidly on the implication of CGRP in primary headache during …
… Evidence has accumulated rapidly on the implication of CGRP in primary headache during …
[HTML][HTML] Investigating migraine-like behavior using light aversion in mice
M Wang, BN Mason, LP Sowers… - Journal of visualized …, 2021 - ncbi.nlm.nih.gov
… in the development of calcitonin gene-related peptide (CGRP) … This procedure has been
used to study the effect of peripheral … can also be used to assess light-aversive behavior as well. …
used to study the effect of peripheral … can also be used to assess light-aversive behavior as well. …
… orexin 1 receptors in the ventrolateral periaqueductal gray matter attenuate nitroglycerin-induced migraine attacks and calcitonin gene related peptide up-regulation in …
… After 10 min, migraine-associated behavioral symptoms were … Calcitonin gene-related
peptide (CGRP)-positive cells were … The effect is indicated by the upregulation of nociceptive …
peptide (CGRP)-positive cells were … The effect is indicated by the upregulation of nociceptive …
Calcitonin gene-related peptide receptor antagonism reduces motion sickness indicators in mouse migraine models
… of calcitonin gene-related peptide (CGRP) or other migraine … The greatest effect of CGRP
and SNP on delta tail … Previous studies assessing CGRP’s effects on light-aversive behavior (…
and SNP on delta tail … Previous studies assessing CGRP’s effects on light-aversive behavior (…
Contribution of intraganglionic CGRP to migraine-like responses in male and female rats
EI Araya, JM Turnes, AR Barroso… - Cephalalgia, 2020 - journals.sagepub.com
… -behavior. Female rats are likely to be more susceptible to calcitonin gene-related peptide
effects … Sexual dichotomy has also been demonstrated in the effect of anti-migraine drugs. It …
effects … Sexual dichotomy has also been demonstrated in the effect of anti-migraine drugs. It …
Neuroanatomical evidence and a mouse calcitonin gene–related peptide model in line with human functional magnetic resonance imaging data support the …
… in migraine. Using RNAscope in situ hybridization and immunostaining, we examined the
expression of calcitonin gene–related peptide … The light-aversive behavior was assessed using …
expression of calcitonin gene–related peptide … The light-aversive behavior was assessed using …