… of the role that CAFs play in conferring therapeutic resistance in different … functions of
CSCs are their role in resistance to multiple anticancer therapies and the repopulation of cancer …

… First, CAFs and their generated ECM can function as a … to tumor progression, affect their
response to clinical therapy … -directed anticancer therapies for lung and pancreatic cancer that …

Fibroblasts play an essential role in organogenesis and the … regulate cancer-associated
inflammation and antitumor immunity, … can confer resistance to immune-based therapies for solid …

… on anticancer therapies. CAFs, as one of the dominant cell types in the tumor stroma, and
their role in anticancer treatments have … At the CAF origin is an individual factor that reveals its …

… of anti-tumor immunity, and resistance to cancer therapy. … their biologic tumor-promoting
functions and recent advancements in the development of CAF-targeting cancer therapies. …

… CAF activation, their multiple origins, and most importantly their role in conferring
chemoresistance. … with utmost importance to unravel the successful strategies of anti-cancer …

… cancer-associated fibroblasts, which have been implicated in diverse oncogenic roles including
cancer invasion and metastasis, resistance to … their significance as modulators of cancer …

… , metastasis and resistance to anticancer therapies are … as well as to their usefulness in
anti-cancer therapies. To date, … establishing their precise role in vivo at different stages of tumor …

… cancer-associated fibroblasts and targeted therapy for cancer | Signal Transduction and
Targeted Therapy … Signaling pathways in cancer-associated fibroblasts and targeted therapy for …

… of studies that support a tumor-promoting function for CAFs, … with their activity as potential
strategies in anticancer therapy. … repetitive damage, fibroblasts become resistant to apoptosis …