Platelets and their role in hemostasis and thrombosis—From physiology to pathophysiology and therapeutic implications
A Scridon - International Journal of Molecular Sciences, 2022 - mdpi.com
… important roles in the arterial circulation, whereas coagulation … In reality, however, this
view of thrombosis oversimplifies a … endothelium, innate immunity, platelets, and coagulation …
view of thrombosis oversimplifies a … endothelium, innate immunity, platelets, and coagulation …
Endothelial cells and coagulation
K Neubauer, B Zieger - Cell and tissue research, 2022 - Springer
… complexes and clotting. This review gives an overview about the central role of the endothelium
as a dynamic lining which controls the complex interplay of the coagulation system with …
as a dynamic lining which controls the complex interplay of the coagulation system with …
The role of red blood cells in hemostasis
AA Alamin - Seminars in thrombosis and hemostasis, 2021 - thieme-connect.com
… Third, the RBC NO synthase (NOS) enzyme, which is localized in the RBC membrane and
cytoplasm, functions similarly to endothelial NOS.[30] Extracorporeal circulation is known to …
cytoplasm, functions similarly to endothelial NOS.[30] Extracorporeal circulation is known to …
[HTML][HTML] The role of thrombin in haemostasis
OM Al-Amer - Blood Coagulation & Fibrinolysis, 2022 - journals.lww.com
… In coagulation system, thrombin has two very distinct roles. … regulation of the blood coagulation
system contains protein C, … In this review, the multiple roles of thrombin in the haemostatic …
system contains protein C, … In this review, the multiple roles of thrombin in the haemostatic …
Disseminated intravascular coagulation: new identity as endotheliopathy-associated vascular microthrombotic disease based on in vivo hemostasis and endothelial …
JC Chang - Thrombosis Journal, 2020 - Springer
… bodily injury, leading to coagulation, and blood clot … to thrombosis. However, a major
dilemma is we cannot reconcile the different role of various coagulation participants in coagulation …
dilemma is we cannot reconcile the different role of various coagulation participants in coagulation …
Thrombin: a pivotal player in hemostasis and beyond
JB Larsen, AM Hvas - Seminars in Thrombosis and Hemostasis, 2021 - thieme-connect.com
… has significant effects beyond hemostasis, as it contributes also to modulation of the
endothelium, promotes inflammation and angiogenesis, and plays a role in tumor progression. Yet, …
endothelium, promotes inflammation and angiogenesis, and plays a role in tumor progression. Yet, …
The vascular endothelium and coagulation: homeostasis, disease, and treatment, with a focus on the von willebrand factor and factors VIII and V
JAD Pablo-Moreno, LJ Serrano, L Revuelta… - International Journal of …, 2022 - mdpi.com
… functions of the vascular endothelium have led to a reassessment of the role of endothelial
cells in the blood-clotting process, with new models being established to explain hemostasis […
cells in the blood-clotting process, with new models being established to explain hemostasis […
Between inflammation and thrombosis: endothelial cells in COVID-19
A Birnhuber, E Fliesser, G Gorkiewicz… - European …, 2021 - Eur Respiratory Soc
… the disease, our data unravel endothelial cell markers that participate in inflammatory cell
recruitment, maintenance of endothelial cell integrity and coagulation in critically ill COVID-19 …
recruitment, maintenance of endothelial cell integrity and coagulation in critically ill COVID-19 …
Red blood cell contribution to hemostasis
AH Gillespie, A Doctor - Frontiers in Pediatrics, 2021 - frontiersin.org
… With regard to hemostatic related mechano-transduction by endothelium, the synthesis of
pro-thrombotic and pro-inflammatory mediators such as Tissue Factor, von Willebrand Factor, …
pro-thrombotic and pro-inflammatory mediators such as Tissue Factor, von Willebrand Factor, …
Recent insights into the regulation of coagulation and thrombosis
X Li, MMS Sim, JP Wood - … , thrombosis, and vascular biology, 2020 - Am Heart Assoc
… endothelial cells. Knockout of TF specifically in vascular smooth muscle cells inhibits thrombus
… Hepatocytes have direct exposure to the plasma because of the fenestrated endothelium …
… Hepatocytes have direct exposure to the plasma because of the fenestrated endothelium …