[HTML][HTML] The inducible nitric oxide synthase pathway promotes osteoclastogenesis under hypoxic culture conditions

T Kondo, Y Otsuka, H Aoki, Y Goto, Y Kawaguchi… - The American Journal of …, 2021 - Elsevier
… investigated the role of inducible nitric oxide synthase (iNOS) in OC differentiation under
hypoxia. … of the iNOS gene, 32 an increase in HIF- due to hypoxia could cause an increase in …

Nitric oxide promotes cerebral ischemia/reperfusion injury through upregulating hypoxia-inducible factor1-α-associated inflammation and apoptosis in rats

N Yang, X Yang, Y Fang, Y Huang, W Shi, W Li… - Neuroscience …, 2023 - Elsevier
HIF- activation during hypoxia and reoxygenation. Given the important role of NO in neuronal
cell death during … cerebral ischemia may induce HIF- expression and lead to I/R injury. …

Hypoxic training improves blood pressure, nitric oxide and hypoxia-inducible factor-1 alpha in hypertensive patients

N Muangritdech, MJ Hamlin, K Sawanyawisuth… - European journal of …, 2020 - Springer
hypoxic effects on nitric oxide metabolism (NOx), HIF- and MDA. We found significant inverse
correlations between both chemicals (NO and HIF-) … for intermittent hypoxic users, our …

The roles of HIF-signaling in cardiovascular diseases

T Sato, N Takeda - Journal of cardiology, 2023 - Elsevier
Hypoxia inducible factor (HIF) switching and nitric oxide (NO) production. HIF- increases
the expression of inducible nitric oxide … HIF-2 elicits the arginase1 (Arg1) expression and …

Nitric oxide-dependent pathways as critical factors in the consequences and recovery after brain ischemic hypoxia

JM Wierońska, P Cieślik, L Kalinowski - Biomolecules, 2021 - mdpi.com
… (NO • ), a molecule that is involved in the regulation of proper … hypoxia-inducible factor
1α (HIF-) and HIF--dependent genes activated in reactive astrocytes play essential roles

Hypoxia-inducible factor 1α from a high-altitude fish enhances cytoprotection and elevates nitric oxide production in hypoxic environment

C Wang, X Wu, X Hu, H Jiang, L Chen, Q Xu - Fish physiology and …, 2020 - Springer
… our extensive understandings of the role of HIF- and iNOS in … In addition, over-expression
of HIF- can prevent hypoxia-… the function of Schizothoracine HIF-/B under hypoxia. Our …

Endothelial dysfunction driven by hypoxia—the influence of oxygen deficiency on NO bioavailability

A Janaszak-Jasiecka, A Siekierzycka, A Płoska… - Biomolecules, 2021 - mdpi.com
HIF- accumulates in the initial phase of hypoxia, while the … , hypoxia affects the nitric oxide
synthesis pathway throughHypoxic signaling diminishes eNOS expression and activity and…

High‐intensity exercise in hypoxia improves endothelial function via increased nitric oxide bioavailability in C57BL/6 mice

J Lavier, M Beaumann, S Menétrey… - Acta …, 2021 - Wiley Online Library
… in normoxia and hypoxia on vascular reactivity and nitric oxide (NO) bioavailability in mice.
… effect of hypoxia independently of exercise training intensity in mRNA expression of HIF- (…

Pharmacological HIF‐PHD inhibition reduces renovascular resistance and increases glomerular filtration by stimulating nitric oxide generation

M Burmakin, A Fasching, H Kobayashi… - Acta …, 2021 - Wiley Online Library
… Although the effects of hypoxia on renal haemodynamics and function have been studied in
… O 2 -regulated α-subunit (either HIF-, HIF-2α or HIF-3α) and a constitutively expressed β-…

The role of nitrite and nitric oxide under low oxygen conditions in plants

KJ Gupta, LAJ Mur, A Wany, A Kumari… - New …, 2020 - Wiley Online Library
… Operation of the phytoglobin/nitric oxide (Pgb/NO) cycle under hypoxic conditions. The
reduction of nitrite to NO occurs at complex III (bc 1 ), complex IV (cytochrome c oxidase) and the …