[HTML][HTML] Poly (ADP-ribose) polymerase-1: an update on its role in diabetic retinopathy
J Sun, L Chen, R Chen, Q Lou… - Discovery …, 2021 - discoverymedicine.com
… retinopathy complications. In the current review, we investigated … roles of PARP-1 in diabetic
retinopathy and its potential applications in diabetic diagnosis and prognosis for purpose of …
retinopathy and its potential applications in diabetic diagnosis and prognosis for purpose of …
Lipoic acid decreases the expression of poly ADP-ribose polymerase and inhibits apoptosis in diabetic rats
J Chen, Q Li - Diabetes, Metabolic Syndrome and Obesity, 2020 - Taylor & Francis
… of diabetic complications including peripheral neuropathy. Citation2 Poly ADP-ribose polymerase
(… an important role in the initiation of apoptosis. Citation3,Citation4 PARP can catalyze …
(… an important role in the initiation of apoptosis. Citation3,Citation4 PARP can catalyze …
Poly (ADP‐ribose) polymerase 1‐mediated defective mitophagy contributes to painful diabetic neuropathy in the db/db model
P Yuan, F Song, P Zhu, K Fan, Q Liao… - Journal of …, 2022 - Wiley Online Library
… Poly ADP-ribose polymerase 1 (PARP1), a sensor of DNA damage, has been reported to
play a key role in DNA damage and repair (Krishnakumar & Kraus, 2010; Langelier et al., 2012)…
play a key role in DNA damage and repair (Krishnakumar & Kraus, 2010; Langelier et al., 2012)…
Role of poly (ADP-ribose) polymerase-1 in regulating human islet cell differentiation
… PARP1 is catalytically activated in response to DNA damage to consume NAD and form
polymers of ADP-ribose (PAR) that … 26 and retinopathy 27 is well documented. In contrast, the …
polymers of ADP-ribose (PAR) that … 26 and retinopathy 27 is well documented. In contrast, the …
'PARP'ing fibrosis: repurposing poly (ADP ribose) polymerase (PARP) inhibitors
… PARP activation was postulated to contribute to fibrosis allied with diabetes-induced nephropathy
through poly … to reduce glomerular fibrosis associated with diabetic nephropathy [24]. …
through poly … to reduce glomerular fibrosis associated with diabetic nephropathy [24]. …
Poly (ADP-ribose) polymerase: an overview of mechanistic approaches and therapeutic opportunities in the management of stroke
… poly (ADP-ribose) polymerase enzyme induces a series of events resulting in polymers of
poly ADP-ribose (… Activation of PARP-1 in the nucleus leads to mitochondrial dysfunction. This …
poly ADP-ribose (… Activation of PARP-1 in the nucleus leads to mitochondrial dysfunction. This …
Poly (ADP-ribose) polymerase 1 and neurodegenerative diseases: past, present, and future
ML Hu, YR Pan, YY Yong, Y Liu, L Yu, DL Qin… - Ageing research …, 2023 - Elsevier
… In this review, we comprehensively synthesize and explore the multifaceted role of PARP1
in neurodegenerative diseases, with a particular emphasis on its over-activation in the …
in neurodegenerative diseases, with a particular emphasis on its over-activation in the …
Diabetic neuropathy: review on molecular mechanisms
MM Sanaye, SA Kavishwar - Current Molecular Medicine, 2023 - ingentaconnect.com
… This review focuses on the pathophysiology of diabetic neuropathy and the possible …
The role of poly(ADP-ribose) polymerase activation in the development of myocardial and …
The role of poly(ADP-ribose) polymerase activation in the development of myocardial and …
Biomarkers in diabetic neuropathy
KM Adki, YA Kulkarni - Archives of Physiology and Biochemistry, 2023 - Taylor & Francis
… of diabetic neuropathies, current diagnosis options of diabetic neuropathy, the pathogenesis
of diabetic neuropathy… Lipoic acid decreases the expression of poly ADP-ribose polymerase …
of diabetic neuropathy… Lipoic acid decreases the expression of poly ADP-ribose polymerase …
NAD+ Precursors Repair Mitochondrial Function in Diabetes and Prevent Experimental Diabetic Neuropathy
K Chandrasekaran, N Najimi, AR Sagi… - International Journal of …, 2022 - mdpi.com
… We tested whether NMN injection could prevent peripheral neuropathy in STZ rats. After
8 weeks of STZ-induced diabetes, rats showed a significant slowing of SMNCV (Figure 1) (from …
8 weeks of STZ-induced diabetes, rats showed a significant slowing of SMNCV (Figure 1) (from …