The critical roles and mechanisms of immune cell death in sepsis

Z Cheng, ST Abrams, J Toh, SS Wang, Z Wang… - Frontiers in …, 2020 - frontiersin.org
… consequences of infection-induced extensive immune cell death during the development of
sepsis. … susceptible to programmed cell death, many other types of immune cells including …

Sepsis-induced immunosuppression: mechanisms, diagnosis and current treatment options

D Liu, SY Huang, JH Sun, HC Zhang, QL Cai… - Military Medical …, 2022 - Springer
… molecules [such as programmed cell death 1 (PD-1), T-cell immunoglobulin and mucin …
A comprehensive understanding of the pathogenesis may provide new ideas and strategies …

Programmed cell death tunes tumor immunity

J Liu, M Hong, Y Li, D Chen, Y Wu, Y Hu - Frontiers in immunology, 2022 - frontiersin.org
… (injury or infection, etc.) states, cells adopt different cell death pathways which generate …
cells die each day to maintain a healthy turnover of cells (48). Programmed Cell Death (PCD…

[HTML][HTML] The potential immunological mechanisms of sepsis

X Zhang, Y Zhang, S Yuan, J Zhang - Frontiers in immunology, 2024 - frontiersin.org
… the role of immune cells, organs, and cell death patterns in the complex organismal homeostasis
of sepsis. … Pyroptosis refers to programmed cell death that is mediated by the gasdermin …

Programming inflammatory cell death for therapy

S Christgen, RE Tweedell, TD Kanneganti - Pharmacology & therapeutics, 2022 - Elsevier
Programmed cell death (PCD) is an essential part of organismal development and plays …
The role of these pathways during development, infection, and disease pathogenesis has …

Emerging connectivity of programmed cell death pathways and its physiological implications

S Bedoui, MJ Herold, A Strasser - Nature reviews Molecular cell biology, 2020 - nature.com
cells is driven by programmed cell death (PCD) pathways, highlighting their important roles
in … is most pronounced in cellular responses to infection, while apoptosis is the dominant …

Immune deregulation in sepsis and septic shock: reversing immune paralysis by targeting PD-1/PD-L1 pathway

Y Nakamori, EJ Park, M Shimaoka - Frontiers in immunology, 2021 - frontiersin.org
… restore immune dysregulation in sepsis has been validated in … the programmed cell death
protein 1/programmed death ligand … The roles of exosomes in the pathogenesis of sepsis have …

The role of death domain proteins in host response upon SARS-CoV-2 infection: modulation of programmed cell death and translational applications

NV Ivanisenko, K Seyrek, NA Kolchanov… - Cell death …, 2020 - nature.com
… of programmed cell death upon SARS-CoV-2 infection remain to … cell death pathways play
a key role in SARS-CoV-2 infection. … in viral pathogenesis and host antiviral response. Many …

[HTML][HTML] Cell death of intestinal epithelial cells in intestinal diseases

S Subramanian, H Geng, XD Tan - Sheng li xue bao:[Acta …, 2020 - ncbi.nlm.nih.gov
… c in villus, compared with septic fabpi-Tag (TAg alone) … programmed cell death, the non-programmed
cell death mechanism also plays a significant role in the pathogenesis of sepsis. …

Defensive strategies of ROS in Programmed Cell Death associated with hypertensive response in plant pathogenesis

N Dey, UK Roy, M Aditya… - Annals of Systems …, 2020 - biolscigroup.us
… Therefore, for true necrotrophic pathogens, such as Botryotinia fuckeliana, it has been
suggested that plant cell death is beneficial for infection, leading to improved colonisation [44]. On …