Therapeutic Potential and Mechanisms of Rosmarinic Acid and the Extracts of Lamiaceae Plants for the Treatment of Fibrosis of Various Organs
YC Boo - Antioxidants, 2024 - mdpi.com
… to discuss the antifibrotic effects of rosmarinic acid (RA) and … , have been shown to
attenuate fibrosis of the liver, kidneys, … apoptosis in the activated hepatic stellate cell line (HSC-T6), …
attenuate fibrosis of the liver, kidneys, … apoptosis in the activated hepatic stellate cell line (HSC-T6), …
Lemon balm and its constituent, rosmarinic acid, alleviate liver damage in an animal model of nonalcoholic steatohepatitis
… , rosmarinic acid (RA), effectively improve the liver … hepatic stellate cells recruit circulating
immune cells and are differentiated to myofibroblasts, which ultimately results in liver fibrosis…
immune cells and are differentiated to myofibroblasts, which ultimately results in liver fibrosis…
SIRT1/NFκB pathway mediates anti-inflammatory and anti-apoptotic effects of rosmarinic acid on in a mouse model of nonalcoholic steatohepatitis (NASH)
T Komeili-Movahhed, M Bassirian… - Journal of Receptors …, 2022 - Taylor & Francis
… 19–21] and attenuates apoptosis and fibrosis in the renal cells, … Rosmarinic acid attenuated
apoptosis pathway related … fact, hepatic lipid accumulation triggers hepatic stellate cells, …
apoptosis pathway related … fact, hepatic lipid accumulation triggers hepatic stellate cells, …
[PDF][PDF] The Effects of Rosmarinic Acid on the Liver Fibrosis Induced by Non-alcoholic Steatohepatitis in Male Mice
A Moslehi, T Komeili-Movahed - Qom University of Medical …, 2021 - scholar.archive.org
… , and hepatocellular carcinoma. Rosmarinic Acid (RA) is a powerful antioxidant and anti-…
role of RA on a mouse model of NASH-induced liver fibrosis. Methods In this research, C57/BL6 …
role of RA on a mouse model of NASH-induced liver fibrosis. Methods In this research, C57/BL6 …
Inhibition of p66Shc oxidative signaling via CA-induced upregulation of miR-203a-3p alleviates liver fibrosis progression
Z Wang, Y Zhao, H Zhao, J Zhou, D Feng… - … Therapy-Nucleic Acids, 2020 - cell.com
… against hepatic stellate cell (HSC) activation during liver fibrosis… means to attenuate the
progression of liver fibrosis. However, … Relevance of carnosic acid, carnosol, and rosmarinic acid …
progression of liver fibrosis. However, … Relevance of carnosic acid, carnosol, and rosmarinic acid …
Rosmarinic acid alleviates toosendanin-induced liver injury through restoration of autophagic flux and lysosomal function by activating JAK2/STAT3/CTSC pathway
L Luo, J Lin, S Chen, J Ni, H Peng, F Shen… - Journal of …, 2024 - Elsevier
… This study demonstrated that RA attenuated TSN-caused … Rosmarinic acid attenuates
hepatic steatosis by modulating ER stress and autophagy in oleic acid-induced HepG2 cells …
hepatic steatosis by modulating ER stress and autophagy in oleic acid-induced HepG2 cells …
A comprehensive review of natural products against liver fibrosis: flavonoids, quinones, lignans, phenols, and acids
X Pan, X Ma, Y Jiang, J Wen, L Yang… - Evidence‐based …, 2020 - Wiley Online Library
… (ECM) accumulation and hepatic stellate cell (HSC) activation. A … mg/kg significantly attenuated
liver damage and liver fibrosis … that rosmarinic acid inhibited liver fibrosis progression by …
liver damage and liver fibrosis … that rosmarinic acid inhibited liver fibrosis progression by …
Rosmarinic acid prevents radiation-induced pulmonary fibrosis through attenuation of ROS/MYPT1/TGFβ1 signaling via miR-19b-3p
T Zhang, S Ma, C Liu, K Hu, M Xu… - Dose-Response, 2020 - journals.sagepub.com
… It has been reported that RA attenuates airway inflammation by mediating the … suppresses
ROS production and lipid peroxidation whereas increases cellular GSH in hepatic stellate cells…
ROS production and lipid peroxidation whereas increases cellular GSH in hepatic stellate cells…
Salvianolic acid B suppresses hepatic fibrosis by inhibiting ceramide glucosyltransferase in hepatic stellate cells
… in the pathogenesis of hepatic fibrosis. We first found that UGCG was over-expressed in
fibrotic livers and activated hepatic stellate cells (HSCs). In human HSC-LX2 cells, inhibition of …
fibrotic livers and activated hepatic stellate cells (HSCs). In human HSC-LX2 cells, inhibition of …
[PDF][PDF] Protective Effect of Rosmarinic Acid on Inflammatory Changes of Hepatic Cells in Non-alcoholic Steatohepatitis in Mice: Cyclooxygenase 2/Prostaglandin E2 …
T Komeili-Movahhed, A Moslehi - Qom Univ Med Sci J, 2023 - sid.ir
Methods In this study, 24 C57/BL6 male mice were used. They were divided into four groups
of 6 including; Control, RA, NASH, and NASH+ RA. The NASH was induced by a methionine…
of 6 including; Control, RA, NASH, and NASH+ RA. The NASH was induced by a methionine…