Porcine sapovirus-induced tight junction dissociation via activation of the RhoA/ROCK/MLC signaling pathway

M Sharif, YB Baek, A Naveed, N Stalin, MI Kang… - Journal of …, 2021 - Am Soc Microbiol
… the RhoA/ROCK/MLC pathway mediates the disruption of TJ … the rotavirus-induced
RhoA/ROCK/MLC signaling pathway. (… early activation of the RhoA/ROCK/MLC signaling pathway

Treading a HOSTile path: mapping the dynamic landscape of host cell–rotavirus interactions to explore novel host-directed curative dimensions

U Patra, U Mukhopadhyay, A Mukherjee, S Dutta… - Virulence, 2021 - Taylor & Francis
… TJ disruption downstream of RhoA/ROCK/MLC signaling. (4) … -mediated Phosphoinositide
3-Kinase (PI3K) activation but … Indeed, inhibition of the RhoA/ROCK/MLC signaling pathway

Rotavirus cell entry: not so simple after all

CF Arias, S López - Current opinion in virology, 2021 - Elsevier
… by signaling through the RhoA/ROCK/MLC pathway, induced by virus attachment to cell
receptors on the apical side, that mediates the disruption of … of these signaling pathways do not …

The Role of Differential Host Glycan Interactions in Rotavirus Cell Entry and Replication

M Raque - 2022 - rave.ohiolink.edu
… viruses by interacting with the early cell attachment stages [… is due to the NSP4-mediated
activation of the enteric nervous … In conclusion, while the IFN-signaling pathway is complex, …

[HTML][HTML] ROCK1/MLC2 inhibition induces decay of viral mRNA in BPXV infected cells

R Kumar, Y Chander, N Khandelwal, A Verma… - Scientific Reports, 2022 - nature.com
The early gene transcription occurs within the viral particles … drugs are based on directly
disrupting the functions of viral … which is mediated via ROCK1/MLC2 cell signaling pathway. …

Live-cell microscopy analysis of rotavirus-infection spread and its associated innate immune response in human intestinal epithelial cells

P Doldan - 2023 - archiv.ub.uni-heidelberg.de
… of cells, and that rotavirus-induced calcium waves alters the … +-mediated positive and
negative feedback signaling can … , in which the formation of tight junctions was disrupted 147. …

Anti-rotavirus properties and mechanisms of selected Gram-positive and Gram-negative probiotics on polarized human colonic (HT-29) cells

A Kumar, YA Helmy, Z Fritts, A Vlasova, LJ Saif… - Probiotics and …, 2022 - Springer
… , cytokine and chemokine mediated signaling pathway, cell … RV infection activates
RhoA/ROCK/MLC signaling, which … ), which is critical in early intestinal differentiation and has …

Sterol regulatory element-binding proteins involved in reprogramming of lipid droplet formation after rotavirus infection

A Naveed, YB Baek, M Soliman, M Sharif… - Korean Journal of …, 2021 - koreascience.kr
Rotavirus-induced SREBP-mediated lipogenic reprogramming … This is partially consistent
with our results showing early … viroplasms, and compounds disrupting or blocking lipid droplets …

Wogonoside alleviates colitis by improving intestinal epithelial barrier function via the MLCK/pMLC2 pathway

S Huang, Y Fu, B Xu, C Liu, Q Wang, S Luo, F Nong… - Phytomedicine, 2020 - Elsevier
… Wogonoside alleviated the disruption of transepithelial electrical resistance (TER) in TNF-α …
effect may be closely associated with the inhibition of the MLCK/pMLC2 signaling pathway. …

[HTML][HTML] Analysis of interaction network between host protein and M protein of swine acute diarrhea syndrome coronavirus

J Xu, Z Cao, C Ji, L Zhou, X Yan, Y Sun… - Frontiers in Microbiology, 2022 - frontiersin.org
… This suggests that M protein may mediate a series of signal transduction … signal pathway,
and other important signal pathways in the host body. It is known that the AMPK signal pathway