Revised subunit order of mammalian septin complexes explains their in vitro polymerization properties

F Soroor, MS Kim, O Palander… - Molecular Biology of …, 2021 - Am Soc Cell Biol
septin octamers, if SEPT9 is located at the terminal position, then SEPT9-SEPT9 … and the
SEPT3 subfamily occupies the terminal position, mutation of the N-terminus should prevent this. …

[HTML][HTML] Structure and function of Septin 9 and its role in human malignant tumors

J Sun, MY Zheng, YW Li, SW Zhang - World Journal of …, 2020 - ncbi.nlm.nih.gov
SEPT9 occupies the ends of mammalian octameric SEPT … SEPT9 mislocalization can mediate
cytokinesis failure and lead to … Elongated N-terminal tail of SEPT9 is enriched with proline …

The structural biology of septins and their filaments: an update

IA Cavini, DA Leonardo, HVD Rosa… - Frontiers in Cell and …, 2021 - frontiersin.org
… ” are depicted on the octamer. Straight arrows represent the … , although the longest isoform
of SEPT9 has an N-domain of … of Asp(Sw2) is mediated by two waters rather than one (PDB:…

Septin-microtubule association requires a MAP-like motif unique to Sept9 isoform 1 embedded into septin octamers

M Kuzmić, GC Linares, JL Fialová, F Iv, D Salaün… - BioRxiv, 2021 - biorxiv.org
… , WS Distinct roles of septins in cytokinesis: SEPT9 mediates midbody abscission. J …
SEPT9 occupies the terminal positions in septin octamers and mediates polymerization-dependent

[图书][B] SEPT9 Binds Actin Through a Novel Binding Motif

RA Rhodes - 2020 - search.proquest.com
… N-terminal region of the NTD as responsible for most of SEPT9’… in the octamer SEPT3 could
be replaced with SEPT9 and still … However, these septin−actin interactions must be mediated

Cellular functions of actin-and microtubule-associated septins

ET Spiliotis, K Nakos - Current Biology, 2021 - cell.com
Septins are an integral component of the cytoskeleton, assembling into higher-order … Here,
we review septin interactions with actin and microtubules, and septin-mediated regulation of …

Septin-microtubule association via a motif unique to isoform 1 of septin 9 tunes stress fibers

M Kuzmić, G Castro Linares… - Journal of cell …, 2022 - journals.biologists.com
… (HNA), mediates the binding of septins to microtubules, but the … N-terminal region (N-ter
common to SEPT9 long isoforms) that … long SEPT9 isoforms incorporate indifferently in octamers. …

Structural Insights into Ciona intestinalis Septins: complexes suggest a mechanism for nucleotide-dependent interfacial cross-talk

DC Mendonça, STB Morais, H Ciol, APA Pinto… - Journal of Molecular …, 2024 - Elsevier
Septin polymerization dependent on CiSEPT2. … differs from the octamer in lacking the two
central (SEPT9) subunits. … or a spring between interfaces mediated by a cluster of aromatic …

An atomic model for the human septin hexamer by cryo-EM

DC Mendonça, SL Guimarães, HDM Pereira… - Journal of molecular …, 2021 - Elsevier
… the exposed interfaces on the terminal subunits. Since these … approximately spherical objects
that occupy a large portion of … current study to include octameric complexes which contain …

Emerging Functions of Septins—Volume II

MB Menon, M Gaestel - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
… for the Septin9 C-terminal region in septin filament assembly. … -3-3 dependent mechanism
for septin-mediated dendritic spine … of septin subunits in the core hexamer and octamer units of …