Phase IIIb safety and efficacy of intravenous NEPA for prevention of chemotherapyinduced nausea and vomiting (CINV) in patients with breast cancer receiving initial …

L Schwartzberg, R Navari, R Clark‐Snow… - The …, 2020 - academic.oup.com
… Different routes of administration of effective and safe drugs increase flexibility and efficiency
Rolapitant IV contains the synthetic surfactant polyoxyl 15 hydroxystearate [26, 31], and HTX…

Prevention of chemotherapy-induced nausea and vomiting in the older patient: optimizing outcomes

J Herrstedt, S Lindberg, PC Petersen - Drugs & aging, 2022 - Springer
… to rolapitant or placebo × 1 on day 1. A significantly higher proportion of patients in the
rolapitant group as compared with the placebo group had CR in the delayed phase (primary effect

Management of chemotherapy-induced nausea and vomiting (CINV): a short review on the role of netupitant-palonosetron (NEPA)

V Lorusso, A Russo, F Giotta, P Codega - Core evidence, 2020 - Taylor & Francis
Rolapitant is a highly selective NK1-RA characterized by … Citation17 Rolapitant also differs
from aprepitant and … to obtain the maximum efficacy in the prophylaxis of CINV. Citation32 …

[PDF][PDF] A Systematic Review of the Management of Chemotherapy-Induced Nausea and Vomiting

JS Raj, S Monisha, MG Rajanandh… - researchgate.net
Safety and efficacy of rolapitant for prevention of chemotherapy-induced nausea and
vomiting after administration of moderately emetogenic chemotherapy or anthracycline and …

[HTML][HTML] Efficacy of intravenous NEPA, a fixed NK1/5-HT3 receptor antagonist combination, for the prevention of chemotherapy-induced nausea and vomiting (CINV) …

M Aapro, RM Navari, E Roeland, L Zhang… - Critical Reviews in …, 2021 - Elsevier
… There are no clinical studies evaluating the efficacy of IV aprepitant/HTX-019 and IV rolapitant
as the approval of these agents was based primarily on demonstrating pharmacokinetic …

Evaluation of Chemotherapy Induced Nausea and Vomiting for Patients Receiving Post-Transplant Cyclophosphamide for Matched Related and Unrelated Donor …

B Andrick, A Potter, A Smith, T Maiers… - Biology of Blood and …, 2020 - tctjournal.org
Prevention of chemotherapy induced nausea and vomiting (… The purpose was to evaluate
episodes of nausea, vomiting, … plus rolapitant was given for CINV prophylaxis during PTCy …

Single-dose fosaprepitant for the prevention of chemotherapy-induced nausea and vomiting in patients receiving moderately emetogenic chemotherapy regimens: a …

C Weinstein, K Jordan, S Green, S Khanani… - BMC cancer, 2020 - Springer
… , CR rates were greater with rolapitant than with active control in the … rolapitant also support
the antiemetic efficacy of a substance P/neurokinin-1 receptor antagonist for the prevention of …

Platinum-induced nausea and vomiting in patients treated for head and neck cancer

A Rambeau, F Cherifi, Z Neviere, I Licaj, B Clarisse… - Bulletin du …, 2021 - Elsevier
prophylaxis before chemotherapy. We aim to assess chemotherapy-induced nausea and
vomiting … The Rolapitant tablets are smaller than the Aprepitant one and were preferred in case …

Netupitant/palonosetron: A review in chemotherapy-induced nausea and vomiting

M Shirley - Drugs, 2021 - Springer
… for the prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV)
in … This article reviews therapeutic efficacy and tolerability data relating to the use of (fos)…

A pragmatic study evaluating NEPA versus aprepitant for prevention of chemotherapy-induced nausea and vomiting in patients receiving moderately emetogenic …

L Zelek, P Debourdeau, H Bourgeois… - The …, 2021 - academic.oup.com
… The primary efficacy endpoint was complete response (no emesis/no rescue) during the …
have acknowledged NEPA and rolapitant as effective agents for decreasing nausea, they also …