… in the same distinct body … immune system development and immune responses in adulthood,
and highlight ongoing work that aims to expand our understanding of the heterogeneity …

… that might affect the generation of immune responses are … We hypothesized that this
myeloid heterogeneity could affect … In addition, we found a similar spatial heterogeneity of OT-I …

… the lymph node sinus system coordinates immune responses … they display extensive
heterogeneity between different sinus … The same mechanism also transferred other large proteins …

… immune response against cancer is orchestrated by various … staining controls (healthy
lymph node) and positive and … The described percentages are similar to our results for other …

… highly similar findings to that … immune response becomes attenuated in node-positive
cancers. Biologically, this would also be predicted; as a tumour progresses the immune response …

… HEVs and disturbed mucosal immune responses (56). Similar processes are also conceivable
… a broad overview of the heterogeneity of ECs throughout several different murine organs, …

… and lymph nodes from the patients’ axilla of the same side (Fig… Biological activities of immune
cells are more intense when … those immune cells in lymph nodes, and immune response …

… ) but additionally generate and fine-tune immune responses that are optimized to the tissue
that they drain. Whether and how other immune … immune responses is currently not known. …

… immune system relies on the generation of diverse immune cell … lymph node and locations
of innate and adaptive immune … see whether similar features are found in T cell responses, or …

… adaptive immune response requires the convergence of multiple cell types in the same …
to survey antigens and mount adaptive immune responses. After pathogen encounter or …