Odontoblast TRPC5 channels signal cold pain in teeth

L Bernal, P Sotelo-Hitschfeld, C König, V Sinica… - Science …, 2021 - science.org
… TRPA1 and TRPM8 to cold-induced tooth pain in vivo were not … jaws and their innervation.
The mandible-inferior alveolar … tooth nerves (27) and when patients perceive pain from tooth

Axolemmal nanoruptures arising from paranodal membrane injury induce secondary axon degeneration in murine Guillain‐Barré syndrome

ME Cunningham, R McGonigal… - … Peripheral Nervous …, 2023 - Wiley Online Library
secondary axonal degeneration, studies have suggested a … anatomical sites that might
induce ischaemic and other injury to … Marie-Tooth diseases, secondary axonal degeneration is …

[HTML][HTML] Demise of nociceptive Schwann cells causes nerve retraction and pain hyperalgesia

P Rinwa, L Calvo-Enrique, MD Zhang, JR Nyengaard… - Pain, 2021 - journals.lww.com
… Our EM results suggest that RTX-induced nerve damage leads to secondary deficits of the …
tissue of innervation. Thus, by delaying cutaneous nerve innervation through a nerve crush in …

Sensory denervation increases potential of bisphosphonates to induce osteonecrosis via disproportionate expression of calcitonin gene–related peptide and …

D Xie, Y Xu, Y Yang, Z Hua, J Li, G Fu… - Annals of the New York …, 2021 - Wiley Online Library
… inferior alveolar nerve injury (IANI) and inferior alveolar nerve … peroxidase-conjugated
secondary antibodies (EMD Millipore). … The first molar was gently luxated using a dental explorer. …

[HTML][HTML] Nervous system-driven osseointegration

R Sun, L Bai, Y Yang, Y Ding, J Zhuang… - International Journal of …, 2022 - mdpi.com
… may enhance innervation and bone regeneration and induce … factor generated from a
target during dental innervation [81]. … In addition to mediating vasodilation, NO is a secondary

Effects of high-frequency near infrared laser irradiation on experimental tooth movement–induced pain in rats

A Nakatani, R Kunimatsu, Y Tsuka, S Sakata… - Lasers in Medical …, 2022 - Springer
… side first molar and incisor in 7-week-old Sprague–Dawley rats (280–300 g) to induce ETM.
… to have significant analgesic effects on ETM-induced pain, which involve inhibiting neuronal …

[HTML][HTML] The special developmental biology of craniofacial tissues enables the understanding of oral and maxillofacial physiology and diseases

M Weber, F Wehrhan, J Deschner, J Sander… - International Journal of …, 2021 - mdpi.com
… , but only induces the development of the nervous system by … from the FNP, the secondary
palate develops from the palatal … Tooth development begins when cells of the oral epithelium …

[HTML][HTML] Neurotrophin signaling is a central mechanism of salivary dysfunction after irradiation that disrupts myoepithelial cells

AM Chibly, VN Patel, MH Aure, MC Pasquale… - NPJ Regenerative …, 2023 - nature.com
… show that nerve growth factor (NGF) induces expression of … that compromise the blood supply
and nerves. Interestingly, ~49% … PBST and incubated in secondary antibodies and nuclear …

Understanding the multi-functionality and tissue-specificity of decellularized dental pulp matrix hydrogels for endodontic regeneration

Z Liang, J Li, H Lin, S Zhang, F Liu, Z Rao, J Chen… - Acta Biomaterialia, 2024 - Elsevier
… After gelation, the encapsulated DPSCs were induced to … were incubated with DyLight 488
secondary antibody (1:800, … ,73], porcine dental pulps and peripheral nerves were chosen as …

Progress in the development of piezoelectric biomaterials for tissue remodeling

A Nain, S Chakraborty, SR Barman, P Gavit… - Biomaterials, 2024 - Elsevier
… Two examples of each tissue, soft (skin and nerve) and hard (dental and bone), are included…
. developed a composite of hydroxyapatite (HA) and BT and examined their bone induction