[PDF][PDF] KEY POINTS IN FERTILITY PRESERVATION TREATMENT STRATEGIES DURING COVID-19 PANDEMIC. AN UPDATE ON PHARMACOLOGICAL …

VN Varlas, RG BORȘ, BA NĂSUI, M Mititelu… - Farmacia, 2021 - researchgate.net
Fertility preservation is urgent by definition, performed for … We performed a systematic search
on fertility preservation (FP) … in ovarian stimulation on fertility preservation studied in the last …

Vilaprisan, a new selective progesterone receptor modulator in uterine fibroid pharmacotherapy-will it really be a breakthrough?

M Ciebiera, SG Vitale, S Ferrero… - Current …, 2020 - ingentaconnect.com
women suffering from symptoms related to UFs [3, 4]. To date, only patients with symptomatic
… (GnRH-a) or selective progesterone receptor modulators (SPRMs) are currently considered …

[PDF][PDF] Role of selective progesterone receptor modulators in the treatment of symptomatic uterine fibroids

N Naresh, P Mani, L Yadav, N Singh - International Journal of …, 2020 - academia.edu
… The most commonly used progesterone receptor modulator is mifepristone (RU486). It …
progesterone receptors, minimally to oestrogen receptors and up regulates androgen receptors. It …

Progesterone signaling and uterine fibroid pathogenesis; molecular mechanisms and potential therapeutics

M Ali, M Ciebiera, S Vafaei, S Alkhrait, HY Chen… - Cells, 2023 - mdpi.com
… of utilizing selective progesterone receptor modulators (… further supports the role progesterone
plays in UF pathogenesis … , and uterine size in 42 women with symptomatic UFs [77]. After …

The selective progesterone receptor modulator ulipristal acetate inhibits the activity of the glucocorticoid receptor

B Small, CEF Millard, EP Kisanga… - The Journal of …, 2020 - academic.oup.com
… The objective of this study was to evaluate the impact of the selective progesterone receptor
modulator ulipristal on glucocorticoid signaling in relevant human cell types. Therefore, we …

Fertility preservation in women with early-stage gynecologic cancer: optimizing oncologic and reproductive outcomes

JL Floyd, S Campbell, JA Rauh-Hain… - International Journal of …, 2021 - ijgc.bmj.com
Preservation of fertility should be discussed with premenopausal women with early-stage
gynecologic cancer shortly after diagnosis and, for women who desire to preserve fertility, …

[PDF][PDF] Ulipristal Acetate-A Selective Progesterone Receptor Modulator

MSM Bashir, KA Bansod, T Khan - jcmad.com
… active drug which is a selective progesterone receptor modulator. Ulipristal acetate also …
that uterine fibroids have progesterone receptors and progesterone activity is responsible for …

Impaired fertility in adenomyosis: a murine model reveals endometrial receptivity and progesterone resistance imbalances

M Squatrito, J Vervier, J Bindels, L Bernet… - …, 2024 - rep.bioscientifica.com
… assess progesterone responsiveness in the uterus of adenomyosis-induced mice, we
examined progesterone receptor … The progesterone receptor was lower expressed in the uteri of …

Treatment choices in a National Cohort of Canadian women with symptomatic uterine fibroids

T Strand, S Kives, N Leyland, J Ashkenas… - Journal of Obstetrics and …, 2020 - Elsevier
… and the selective progesterone receptor modulator ulipristal … Fertility preservation was also
strongly predictive of treatment … to undergo hysterectomy, women expressing no interest in …

Key to life: physiological role and clinical implications of progesterone

B Nagy, J Szekeres-Barthó, GL Kovács… - International journal of …, 2021 - mdpi.com
Progesterone can provide symptom relief from sleep disturbance and mood instability and
progesterone does not cause breast cancer. Selective progesterone receptor modulators