Selenium nanoparticles for biomedical applications: from development and characterization to therapeutics

C Ferro, HF Florindo, HA Santos - Advanced healthcare …, 2021 - Wiley Online Library
… and animals, while selenocysteine mainly exists in animal … several cancer cells, such as
HepG2 (human liver carcinomacancer cells), and A549 cells (lung carcinoma cells). Thereby…

… Structural Characterization of Selenium Nanoparticle Composites Modified by Astragalus Polysaccharide and the Cytotoxicity Mechanism on Liver Cancer Cells

H Ji, X Lou, J Jiao, Y Li, K Dai, X Jia - Molecules, 2023 - mdpi.com
Selenium nanoparticles (SeNPs) have received growing attention in various fields, but
their unstable property increases the application … inhibitory mechanism on liver cancer (HepG2) …

Selenium-Containing Agents Acting on Cancer—A New Hope?

S Garbo, S Di Giacomo, D Łażewska… - Pharmaceutics, 2022 - mdpi.com
… been described to exhibit chemopreventive and antioxidant … plants and animals, selenium
occurs as organic selenium in … application is sometimes limited owing to their possible side …

Selenium nanoparticles overcomes sorafenib resistance in thioacetamide induced hepatocellular carcinoma in rats by modulation of mTOR, NF-κB pathways and …

TM Al-Noshokaty, NM Mesbah, DM Abo-Elmatty… - Life Sciences, 2022 - Elsevier
… to cancer in men, and the third most prevalent cause of death in both sexes [1]. Almost 75%
of all liver cancers are caused by hepatocellular carcinoma … Reducing the number of animals

Selenium and selenoproteins: It's role in regulation of inflammation

S Hariharan, S Dharmaraj - Inflammopharmacology, 2020 - Springer
… to various animal models and cell lines. In this review, the role of selenium and its possible
… range for lung, breast, cervical, liver cancer cells and also in melanoma cells. Cytotoxicity of …

The role and mechanisms of selenium supplementation on fatty liver-associated disorder

L Xu, Y Lu, N Wang, Y Feng - Antioxidants, 2022 - mdpi.com
… For clinical application, selenium can be used to treat erosive oral … could be investigated as
chemoprevention or supplementary therapy … The role of selenium in animal models has been …

Small molecule selenium-containing compounds: Recent development and therapeutic applications

H Chuai, SQ Zhang, H Bai, J Li, Y Wang, J Sun… - European Journal of …, 2021 - Elsevier
carcinoma, acute myeloid leukemia cells and colorectal, lung, breast, liver cancer cells with
… of invasive prostate cancer, but potential toxicity was observed in animals. Therefore, further …

Current Trends on the Involvement of Zinc, Copper, and Selenium in the Process of Hepatocarcinogenesis

T Himoto, T Masaki - Nutrients, 2024 - mdpi.com
… The clinical application of these agents is an urgent unmet … also not associated with the risk
of liver cancer in China [46]. … been developed as an experimental animal mode of Wilson’s …

Food sources of selenium and its relationship with chronic diseases

W Hu, C Zhao, H Hu, S Yin - Nutrients, 2021 - mdpi.com
… plant Se metabolites are consumed by humans and animals. … Foliar spray and soil application
increased the total and … chemopreventive agent for breast cancer in postmenopausal …

The role of selenium nanoparticles in the treatment of liver pathologies of various natures

MV Goltyaev, EG Varlamova - International journal of molecular sciences, 2023 - mdpi.com
liver cell culture and in vivo on animal models. Data were obtained on the direct cytotoxic
effect of Se on liver cancer … difficult task, especially for applications in nanomedicine. In addition…