Cognitive-enhancing effects of acetylcholine receptor agonists in group-housed cynomolgus monkeys who drink ethanol

LK Galbo-Thomma, PM Epperly, BE Blough… - … of Pharmacology and …, 2024 - ASPET
… In the present studies, a scopolamine reversal paradigm was … -housed monkeys with long-term
ethanol self-administration … , individually housed rhesus monkeys, initial performance on …

Novel pharmacological agents for the treatment of cocaine use disorder

H Hadizadeh, J Flores, E Nunes, T Mayerson… - Current Behavioral …, 2022 - Springer
… other cocaine self-administration tests using rhesus monkeys… action of scopolamine on
cocaine use behaviors in rodents. … (eg, a combination of cocaine derivative with protein bovine …

Effects of ecgonine methyl ester on cognition in scopolamine-impaired and aged rats

SH Curry, M Marler - Psychopharmacology, 2020 - Springer
… impairment caused by cocaine in aged rats, this work shows that cocaine and EME … /scopolamine
combination group and the control or EME group, we were left with the scopolamine

Methocinnamox (MCAM) antagonizes the behavioral suppressant effects of morphine without impairing delayed matching-to-sample accuracy in rhesus monkeys

V Minervini, A Disney, SM Husbands, CP France - Psychopharmacology, 2020 - Springer
… intravenous self-administration of opioids in rhesus monkeys for a … as percent correct
matches after scopolamine (a) or … after scopolamine (b) or phencyclidine (d) for five monkeys

NLX-112, a highly selective 5-HT1A receptor biased agonist, does not exhibit misuse potential in male rats or macaques

R Depoortère, J Bergman, PM Beardsley, RI Desai… - …, 2022 - Elsevier
… produced by cocaine in Rhesus macaque monkeys (individual … In the present study, the
combination of low doses of NLX-… on previous rat CPP and iv self-administration assays), it may …

Biperiden reverses the increase in 50-kHz ultrasonic vocalizations but not the increase in locomotor activity induced by cocaine

TCS Saldanha, WN Sanchez, P Palombo… - Behavioural Brain …, 2024 - Elsevier
… of cocaine use disorder (CUD) affecting approximately 21 million people worldwide [2]. Cocaine
Cocaine self-administration can also increase acetylcholine levels in NAc [6]. Therefore, …

Behavioral shaping of rhesus macaques using the Cambridge neuropsychological automated testing battery

RG Wither, SE Boehnke, A Lablans… - Journal of Neuroscience …, 2020 - Elsevier
… that were used to accelerate the training of rhesus macaques on the SOSS, DMTS, and PAL
CANTAB tasks. We used a combination of behavioral shaping and sequential task training …

The role of glutamate mGlu5 and adenosine A2a receptor interactions in regulating working memory performance and persistent cocaine seeking in rats

PU Hámor, CM Gobin, M Schwendt - Progress in Neuro …, 2020 - Elsevier
… of cocaine self-administration. Based on published evidence, we predicted that any drug
combination … of cognitive consequences of chronic cocaine self-administration. Establishing the …

Effects of biperiden (cholinergic muscarinic m1/m4 receptor antagonist) on ethanol conditioned place preference in mice

P Palombo, SA Engi, TS Yokoyama, AG Bezerra… - Neuroscience …, 2021 - Elsevier
… 20] trained rhesus monkeys to self-administer cocaine and observed that … cocaine self-administration
also reduced in rhesus monkeys using another muscarinic antagonist, scopolamine

Sex differences in the effects of a combined behavioral and pharmacological treatment strategy for cocaine relapse prevention in an animal model of cue exposure …

KM Kantak, JM Gauthier, E Mathieson… - Behavioural brain …, 2020 - Elsevier
cocaine delivery and cue presentation in rats and monkeys [… in combination with extinction
training to inhibit cocaine relapse … in self-administration of 1.0 mg/kg cocaine produced by the …