Toward a better understanding of metabolic and pharmacokinetic characteristics of low-solubility, low-permeability natural medicines
J Yang, K Li, D He, J Gu, J Xu, J Xie… - Drug Metabolism …, 2020 - Taylor & Francis
… pharmacokinetic models are comprehensively evaluated. This … For example, a self-microemulsifying
delivery system of … liposomal formulation enhanced the C max of oleanolic acid by …
delivery system of … liposomal formulation enhanced the C max of oleanolic acid by …
From Xanthine Oxidase Inhibition to In Vivo Hypouricemic Effect: An Integrated Overview of In Vitro and In Vivo Studies with Focus on Natural Molecules and …
JL Serrano, J Figueiredo, P Almeida… - … Alternative Medicine, 2020 - Wiley Online Library
… –loaded self-microemulsifying drug delivery system led to an … Given its potential as a
hypouricemic agent, ursolic acid is … further pharmacological evaluation, it is clear in this review that …
hypouricemic agent, ursolic acid is … further pharmacological evaluation, it is clear in this review that …
Unification of medicines and excipients: The roles of natural excipients for promoting drug delivery
M Feng, X Dai, C Yang, Y Zhang, Y Tian… - … on Drug Delivery, 2023 - Taylor & Francis
… The comparison of the drug delivery systems formed by NACs … oral administration can often
significantly improve the gastrointestinal absorption of drugs to obtain high oral bioavailability…
significantly improve the gastrointestinal absorption of drugs to obtain high oral bioavailability…
Transdermal delivery of indirubin-loaded microemulsion gel: preparation, characterization and anti-psoriatic activity
E He, H Li, X Li, X Wu, K Lei, Y Diao - International journal of molecular …, 2022 - mdpi.com
… The present study intended to prepare and evaluate a … concentration, the self-microemulsifying
region was increased, and … drug delivery carrier to increase the transdermal flow of drugs, …
region was increased, and … drug delivery carrier to increase the transdermal flow of drugs, …
Development of phytochemical delivery systems by nano-suspension and nano-emulsion techniques
G Zuccari, S Alfei - International Journal of Molecular Sciences, 2023 - mdpi.com
… oleanolic acid (OA) NSs (SEOA NSs) for enhanced delivery … drug delivery systems (SNEDDSs)
and self-microemulsifying … al. to improve RES bioavailability and was evaluated for its anti-…
and self-microemulsifying … al. to improve RES bioavailability and was evaluated for its anti-…
[HTML][HTML] Lomustine's nanoemulsion as nose-to-brain drug delivery system for CNS tumor treatment
MH Alaayedi, NK Maraie - Saudi Pharmaceutical Journal, 2023 - Elsevier
… drug lomustine had poor oral bioavailability in … improve solubility, avoiding first pass drug
metabolism and reduce systemic side effect of this chemotherapeutic agent as well as evaluate …
metabolism and reduce systemic side effect of this chemotherapeutic agent as well as evaluate …
[HTML][HTML] Physical characterization of clove oil based self Nano-emulsifying formulations of cefpodoxime proxetil: Assessment of dissolution rate, antioxidant & …
… The present work aims to improve CPD solubilization by … , still it has low bioavailability. Since
CPD has aqueous … been utilized in the designing of lipid-based drug delivery systems as a …
CPD has aqueous … been utilized in the designing of lipid-based drug delivery systems as a …
Development and optimization of nanoemulsion containing exemestane using box-behnken design
S Chaturvedi, A Garg - Journal of Drug Delivery Science and Technology, 2023 - Elsevier
… [9], self-microemulsifying drug delivery systems [10], … been investigated for improving the
oral bioavailability of EXE and … every individual run was statistically evaluated using Analysis of …
oral bioavailability of EXE and … every individual run was statistically evaluated using Analysis of …
Nanotechnology in Nutraceuticals Delivery for the Prevention and Treatment of Cancer
OE Eyupoglu, K Saleem - Nutraceuticals in Cancer Prevention …, 2024 - taylorfrancis.com
… Similarly, nanoemulsions of ursolic and oleanic acid improved … Enhanced oral bioavailability
and improved biological … using a liquid self-microemulsifying drug delivery system. Planta …
and improved biological … using a liquid self-microemulsifying drug delivery system. Planta …
Lipid based nanoparticles as a novel treatment modality for hepatocellular carcinoma: a comprehensive review on targeting and recent advances
… low drug bioavailability, and nonspecific drug delivery which … was entrapped with oleanolic
acid in liposomal formulation … model was used for the in vivo evaluation. The presence of …
acid in liposomal formulation … model was used for the in vivo evaluation. The presence of …