Cumulative evidence for relationships between multiple variants in the TERT and CLPTM1L region and risk of cancer and non-cancer disease
J Tian, Y Wang, Y Dong, J Chang, Y Wu… - Frontiers in …, 2022 - frontiersin.org
… genes might demonstrate the observed findings in these loci. … of 23 variants in TERT-CLPTM1L
region with 12 cancers and … four variants associated with risk of bladder and lung cancer …
region with 12 cancers and … four variants associated with risk of bladder and lung cancer …
TERT-rs33963617 and CLPTM1L-rs77518573 reduce the risk of non-small cell lung cancer in Chinese population
Z Ji, Y Li, C Xiang, X Luo, P Yuan, J Long, N Shen… - Gene, 2020 - Elsevier
… locus which associated with a variety of tumors such as lung … the TERT-CLPTM1L region
and got an overview about the landscape of germline variations, including both the common …
and got an overview about the landscape of germline variations, including both the common …
Study of genetic variants in chromosome 5p15. 33 region in non-smoker lung cancer patients
I Mandour, SAM Hussein, R Essam… - Advances in Respiratory …, 2020 - mdpi.com
… [17] have established that locus on chromosome 5p15.33 is distinctly associated with a risk
… common genetic variants in TERT-CLPTM1L locus on chromosome 5p15.33 are associated …
… common genetic variants in TERT-CLPTM1L locus on chromosome 5p15.33 are associated …
Integrated Analysis of Altered lncRNA, circRNA, microRNA, and mRNA Expression in Hepatocellular Carcinoma Carrying TERT Promoter Mutations
H Zhang, X Zhang, J Yu - Journal of Hepatocellular Carcinoma, 2022 - Taylor & Francis
… are one of the most common mutations responsible for the … ) in the TERT-CLPTM1L locus
have been revealed to be significantly associated with the risk of developing different cancers. …
have been revealed to be significantly associated with the risk of developing different cancers. …
The Prognostic Significance of TERT Locus Polymorphism (rs36115365) in Surgically Resected Non-Small Cell Lung Cancer
… (NSCLC), and current articles focused on telomere associated … polymorphism of the
TERT-CLPTM1L locus in NSCLC. The … cancer is known as one of the most well characterized type …
TERT-CLPTM1L locus in NSCLC. The … cancer is known as one of the most well characterized type …
Six minor allele variants in the TERT-CLPTM1L region are associated with lung cancer risk: a meta-analysis based on different ethnicities and different lung cancer …
X Wu, W Li, Z Luo, Y Chen - 2023 - researchsquare.com
… had identi ed dozens of risk loci for LC, and most of these loci were concentrated in 5p15.33 …
Our results con rmed that 6 polymorphisms in TERT-CLPTM1L were associated with the risk …
Our results con rmed that 6 polymorphisms in TERT-CLPTM1L were associated with the risk …
[HTML][HTML] Single nucleotide variants in lung cancer
X Tian, Z Liu - Chinese Medical Journal Pulmonary and Critical Care …, 2024 - Elsevier
… variants in coding exons have been associated with susceptibility or treatment response of
lung cancer. For … To date, 51 lung cancer-associated SNP loci have been identified, 32 and a …
lung cancer. For … To date, 51 lung cancer-associated SNP loci have been identified, 32 and a …
[PDF][PDF] Large-scale cross-cancer fine-mapping of the 5p15. 33 region reveals multiple independent signals
… pleiotropic locus, where genetic variants have been associated with … key genetic variants
related to multiple cancer types. Indeed, … by the TERT-CLPTM1L region in cancer development. …
related to multiple cancer types. Indeed, … by the TERT-CLPTM1L region in cancer development. …
[HTML][HTML] TERT genetic polymorphism rs2736100 is associated with an aggressive manifestation of papillary thyroid carcinoma
X Nie, J Shang, W Wang - Frontiers in Surgery, 2023 - frontiersin.org
… region (TERT-CLPTM1L) is a common susceptibility locus of … However, the involvement of
this locus in the etiology of PTC … -susceptible genetic variants in the TERT-CLPTM1L locus and …
this locus in the etiology of PTC … -susceptible genetic variants in the TERT-CLPTM1L locus and …
[PDF][PDF] Functional characterization of 5p15. 33 risk locus in uveal melanoma reveals rs452384 as a functional variant and NKX2. 4 as an allele-specific interactor
AC Derrien, A Houy, O Ganier, F Dingli… - The American Journal of …, 2022 - cell.com
… for the TERT/CLPTM1L risk locus in this intraocular tumor and … TERT/CLPTM1L locus, we
functionally characterized the … genomic region along with highly correlated variants associated …
functionally characterized the … genomic region along with highly correlated variants associated …