Insulin Therapy:“When Saviour Turns Hostile”

DSMVH Nagarajappaa, SOSSM Srinivasc, R Palanya - 2022 - karger.com
… Additives in insulin preparations, such as protamine, zinc, and cresol, have been shown
to … Severe adverse cutaneous reaction to insulin due to cresol sensitivity. Contact Dermatitis. …

Insulin

CD Paavola, MR De Felippis, DP Allen, A Garg… - Pharmaceutical …, 2024 - Springer
… that incorporates zinc and m-cresol (anti-microbial preservative)… severe insulin resistance.
As discussed above, many human … HMWPs are the most sensitive indicator of photo instability. …

[HTML][HTML] Case report: Insulin desensitization as the only option for managing insulin allergy in a Sudanese patient

R Said, R Goda, IB Abdalrahman, NHH Erwa - Frontiers in Allergy, 2023 - frontiersin.org
… and severe immediate hypersensitivity reactions to insulin, … like cresol and phenol, or the
insulin molecule itself (6, 7). … Allergy skin tests were not performed due to insufficient equipment …

[PDF][PDF] Subcutaneous Injectable Drugs Hypersensitivity and Desensitization

S Bavbek, MJ Lee - academia.edu
related to insulin with brief discussion of ISRs. … Cresol also has been used for skin prick
testing at 1.5 to 3 mg/mL.If there is a suspicion for latex sensitivity, latex-specific IgE and/or skin

Lipohypertrophy and Insulin. An Old Dog that Needs New Tricks

J Huang, AM Yeung, D Kerr, S Gentile, L Heinemann… - Endocrine Practice, 2023 - Elsevier
insulin therapy using impure insulin formulations, local skin … causing acute/chronic inflammation
and insulin degradation … of LH was not sufficiently sensitive or specific for widespread …

Uremic toxicity

R Vanholder, G Glorieux - Handbook of Dialysis Therapy, 2023 - Elsevier
… , p-cresol, was the representative cresol during uremic retention. … Indoxyl sulfate has also
been related to more severe … , such as: restricted insulin release and blunted insulin sensitivity, …

Biologics: Monoclonal Antibodies for Non-cancer Therapy, Cytokines, Fusion Proteins, Enzymes, and Hormones

BA Baldo, NH Pham, BA Baldo, NH Pham - Drug Allergy: Clinical Aspects …, 2021 - Springer
… half-life and susceptibility to proteolysis due to its extended hinge … the presence of negative
skin tests to the glycoprotein, and acute … following skin breakdown due to the insulin excipient …

[HTML][HTML] Weizmannia coagulans strain SANK70258 combined with galacto-oligosaccharides reduces fecal-p-cresol content and improves scaliness and skin …

N Togawa, R Yamada, K Numano, Y Aoki… - Journal of Functional …, 2023 - Elsevier
… with seriousskin roughness and lower p-cresol and p-cresol-related bacterial levels in
the combined group (lac + gal) compared to the lac-alone group (lac + dex). For p-cresol-related

Hypoglycaemic Drugs

U Hariharan, SB Shah, K Sodhi - Principles and Practice of Neurocritical …, 2024 - Springer
… the skin, on pressing a button, the insulin is pushed through. … Insulin is contraindicated in
patients with cresol sensitivity as … benefit of insulin therapy during acute stroke management [28]…

Intranasal insulin

M Hallschmid - Journal of neuroendocrinology, 2021 - Wiley Online Library
… Levemir) that contain m-cresol (meta-cresol), an excipient with … idea that the sensitivity to
the anorexigenic impact of insulin is … of IN insulin on fear extinction turned out to pertain to skin