… briefly examine microglial P2X4R signaling in the spinal cord as it relates to chronic pain
through … Given the distinct microglial response to ATP in males and females, it was important to …

… neuropathic microglial signature and indicates distinct sex … of cytokine signaling 1), whereas
female microglia include … Neuroimmune sex-dependent differences in pain processing …

… in a sex-dependent manner to influence the chronic pain phenotype. In … of cancer pain may
require several functionally distinct … underlying sex-dependent differences in pain signaling is …

… molecular signals that drive the generation and resolution of … These observations suggest
sex-dependent … with chronic pain, and single-cell RNA sequencing of microglia from human …

… The distinct roles of diverse microglia challenge previous … SDH pain network involving
alterations in neurons and glial cells, … + microglia have an ongoing role in painrepressing signals …

… in chronic pain disorders, preclinical pain studies have … disorders, potentially through
sex-dependent hormonal influences. … to many different neurochemicals and signaling molecules. …

… in different models of neuropathic pain, indicating the critical … inhibitor of microglia, and
inhibitors of key signaling molecules … determine the sex-dependent roles of spinal microglia and …

… macrophages may utilize signaling distinct from microglia to modulate chronic pain. In …
neuropathic pain in male but not female mice: sex-dependent microglial signaling in the spinal …

… unique microglia transcriptional profile that is associated with … Microglia differentiate in a
sex-dependent fashion in the … peripheral signals and microglia, and orchestrate disruption of …

… spinal TLR4 mediates inflammatory and neuropathic pain in … signaling through microglial
activation in a sex-dependent fashion. … 2 different approaches to inhibit microglial function, and …