… polarization plays different roles in inducing and resolving pain. … microglial signaling in
inflammatory and neuropathic pain. … This sex-dependent mechanical pain is mediated by the pro-…

… when interpreting the effects of TLR4 signaling in disease pathology. To begin to dissect the
sex- … Contribution of macrophages and microglia in nerve injury-induced neuropathic pain …

… tertiary mediators in signaling of neuropathic pain. Sources of … mechanism is crucial to glial
signaling and the development … hyperalgesia in two different neuropathic pain models (341). …

… are time- and sex-dependent differences in microglial transcriptome. … The findings in this
thesis are shown in two different … Microglia are glial cells that act, in part, as the primary immune …

… a sex-dependent role of the P2X4 receptor in spinal microglia … that microglial P2X4 and
BDNF/TrkB signaling contribute to … dorsal horn of the spinal cord of the different mice. As shown …

… dimorphism in microglial contribution to pain signalling, … In addition, distinct roles of meningeal
layers have been shown in … Our finding of a robust sex-dependent microglial response to …

… signal which is transmitted to the dorsal horn of the spinal cord … PSNs are exclusively
glutamatergic and project to different … nociceptors with distinct roles in neuropathic pain, itch and …

… are required for AcGP in late-onset and sex-dependent … understanding of mechanisms for
neuropathic pain (NeuP) has … brain microglia on AcGP in mice, by using three different types …

… the role of spinal microglia and p38 MAPK signaling in the … allodynia in different models
of neuropathic pain, including … are sex-dependent differences in the expression of microglia …

… OA is the major cause of chronic pain in adults, with pain being … From there, the painful
signal is conveyed by extending … mechanisms of the sex-dependent role of microglia and TLR4 …