… and neuropathic pain mechanisms for these reasons. … addressed specific signaling pathways
involved in glia activation (… of spinal cord microglia did not show differences in microglia …

… Sex- dependent changes in immune signaling in the brain … significant age- and sex-
dependent changes in immune cell … contributors to neuroinflammatory pathology: microglia and T …

… in both sexes, there is strong evidence that inhibiting microglia … about the glial contribution
to chronic pain emanates from … Two different devices were used to induce the injury. Animals …

… of the nociplastic pain state, indicating that spinal microglia … signaling have also been found
to alter microglia function, … reactive spinal microglia are a common culprit for chronic pain …

… comparable p38MAPK levels in the lumbar spinal cord (SC) (… sTNF/TNFR1 signaling nexus
in a sex-dependent manner. More … Microglial activity via p38MAPK signaling was previously …

… to be pivotal in neuropathic pain induction in male rodents upon … the sex-dependent
molecular aspects of spinal microglia in … signaling molecules in the spinal cord microglia-to-neuron …

… and microgliosis) seems to play distinct roles (10, 15). Gliosis is … that pathological pain in
males is regulated by microglial … a sex-dependent nature in inflammatory and neuropathic pain …

… neuropathic pain in the disease. It has been postulated that … disease, TNFα signaling,
mitochondrial function, neuronal injury… microglia/macrophages are responsible for pain in the male …

… was also sex dependent. To this end, we compared the CNO … the following differences: 1)
Different cre mouse lines. Saika … -principle that Gi signaling in microglia can suppress their pro…

… spinal microglia are a common culprit for chronic pain in … a significant role of this purinergic
signaling pathway in microglia … of sex-dependent spinal microglia activation by LTMR inputs. …