… short-term HFD on patterns in genome-wide DNA methylation of CpG sites associated with
human skeletal muscle genes results in high … size, cytology, and morphology that adipocytes …

… which are abundant during highfat feeding, adipose tissue … skeletal muscle mitochondrial
lipid composition, morphology … for energy production during shortterm exercise, this method …

… such as skeletal muscle and bone. While this metabolic shift is advantageous in the short
term, … with respect to body weight, body composition and adipose tissue morphology (51, 98). …

… the effects of training and nutrition on skeletal muscle energy … oxidation after adaptation to
a short-term high-fat diet, even … , high-intensity exercise performance is impaired on the high-…

… the deleterious effects of 8 weeks of high-fat feeding, principally … In parallel with metabolic
adaptation, Canto et al. reported … Recently, we have investigated the effect of short-term NR …

… shown that maternal high-fat feeding results in adult offspring … adaptations in mothers, as
shown by increased skeletal … harmful effects of a maternal high-fat diet on placental morphology …

… high-fat feeding, but unexpectedly, does not exacerbate diet-induced IR (37). Moreover,
short-term … These metabolic adaptations were regulated, at least in part, via ATF4-mediated …

… ) elicits analogous metabolic adaptations in skeletal muscle … employed short-term endurance
exercise bouts or short-term maximal … We hypothesized that a high-fat feeding diet would …

… the impairments of a short-term HF diet on skeletal muscle … modulatory effects that the gut
microbiota has on skeletal muscle … mediating its beneficial metabolic effects on skeletal muscle. …

… The aim of this thesis was to study the effects of short-term … and sternum and lower in long
bones of the extremities. Already two … BM adipocytes (BMAds) share similar morphological …