Diet-induced obesity results in endothelial cell desensitization to VEGF-A and permanent islet vascular dysfunction

Y Xiong, A Dicker, M Visa, E Ilegems, PO Berggren - bioRxiv, 2023 - biorxiv.org
… , and half of the cells were stimulated with 50 ng/ml human VEGF-A (Peprotech, … VEGF-A
sensitivity in the WD and refed groups of mice is due to excessive 563 neutralization of VEGF-A

Hyperglycaemia up-regulates placental growth factor (PlGF) expression and secretion in endothelial cells via suppression of PI3 kinase-Akt signalling and activation …

S Sissaoui, S Egginton, L Ting, A Ahmed… - Scientific Reports, 2021 - nature.com
… expression to those activated by VEGF-A 12 . The expression of … levels in patients with
proliferative diabetic retinopathy 13 , … Using siRNA-mediated knock-down or over-expression of …

Why should growth hormone (GH) be considered a promising therapeutic agent for arteriogenesis? Insights from the GHAS trial

D Caicedo, P Devesa, CV Alvarez, J Devesa - Cells, 2020 - mdpi.com
… A (VEGF-A) [61,62], a factor that plays many roles in cell differentiation, proliferation, and …
dependent vasodilation because hemodynamic or short-term compensation always runs before …

High glucose concentration produces a short-term increase in pERK1/2 and p85 proteins, having a direct angiogenetic effect by an action similar to VEGF

FC Sasso, C Zuchegna, MF Tecce, A Capasso… - Acta Diabetologica, 2020 - Springer
… In addition to metabolic and indirect consequences, … glucose on cultured TIME cells
morphology and proliferation, we used … diabetes, and there are high levels of VEGF-A in the …

VEGF‐B signaling impairs endothelial glucose transcytosis by decreasing membrane cholesterol content

…, I Nilsson, L Muhl, M Zeitelhofer, B Heller Sahlgren… - EMBO …, 2020 - embopress.org
… for energy production, proliferating ECs employ FAs and fatty acid … Short-term (1 week)
2H10-treated HFD mice showed … cells (HUVEC) treated for 10 min and 2 h with VEGF-A 165 (A165…

[PDF][PDF] … Necessary for Glucocorticoids Which Necessary for Interferons Synthesis and Serotonin Synthesis then Promote Ang2-At2 and VEGF-A for Anti-Inflammatory …

AM El Tantawi - Stem Cells Regen Med, 2022 - scivisionpub.com
… growth including Increasing in circulating memory B cells. … respectively), that also proliferation
can be activated by either … large B-cell lymphoma (DLBCL) due to overexpressed the …

Molecular mechanism of VEGF and its role in pathological angiogenesis

A Ahmad, MI Nawaz - Journal of Cellular Biochemistry, 2022 - Wiley Online Library
… , VEGF-A promotes vascular smooth muscle cell proliferation … Furthermore, according to
the ETDRS criteria, short-term … on activated T cells, B cells, macrophages, regulatory T cells, …

Human organ rejuvenation by VEGF-A: Lessons from the skin

A Keren, M Bertolini, Y Keren, Y Ullmann, R Paus… - Science …, 2022 - science.org
… These short-term ex vivo pilot experiments show that … , as well as the proliferation and
differentiation of epidermal … long-term VEGF-A overexpression because chronic VEGF-A receptor …

Vagus nerve stimulation optimized cardiomyocyte phenotype, sarcomere organization and energy metabolism in infarcted heart through FoxO3A-VEGF signaling

B Luo, Y Wu, S Liu, X Li, H Zhu, L Zhang, F Zheng… - Cell death & …, 2020 - nature.com
… the specific effects of ACh on the expression of VEGF-A/B, α/β-MHC, … from proliferation to
differentiation medium at cell confluence. … In line with the changes that short-term Akt1 activation-…

[PDF][PDF] Vascular endothelial growth factor B interferes with angiogenesis and the electrical functions of the heart: pre-clinical studies of intramyocardial gene therapy

OP Hätinen - 2020 - erepo.uef.fi
… between VEGF-B and VEGF-A in promoter regions (Silins … endothelial cell migration,
tube formation, and proliferation. … lifetime overexpression in transgenic mice or the short-term