Design and fabrication of organ-on-chips: promises and challenges

A Tajeddin, N Mustafaoglu - Micromachines, 2021 - mdpi.com
… and silicon-based compositions) are used to fabricate them [93… As they have linear and
branched molecules, they are more … Moreover, liver microvessels are sinusoidal and have mainly …

Microfluidics in vascular biology research: a critical review for engineers, biologists, and clinicians

G Simitian, M Virumbrales-Muñoz… - Lab on a Chip, 2022 - pubs.rsc.org
… described in this review to fabricate microfluidic devices. (A) Soft … affecting vascular systems
and distant organs, including liver … of vascular pruning and regression of selected branches. …

Design and Organization of 3D Tissues with Branching/Joining Flow Channel Network Based on Oxygen Transfer

Y Pang, J Ji, Y Sakai - EMERGING TECHNOLOGIES IN …, 2023 - World Scientific
… This chapter introduces the design and fabrication of 3D tissues with branching network-…
, Silicon micromachining to tissue engineer branched vascular channels for liver fabrication. …

Beyond polydimethylsiloxane: alternative materials for fabrication of organ-on-a-chip devices and microphysiological systems

SB Campbell, Q Wu, J Yazbeck, C Liu… - … & engineering, 2020 - ACS Publications
fabrication using silicon allowed this system to include functional readouts for four tissues:
albumin and urea production in liver … model with a highly branched vascular network in which …

Microfluidic devices in tissue engineering

S Bahrami, N Baheiraei, M Najafi-Ashtiani… - … of Microfluidic Devices, 2021 - Elsevier
… MEMS involve several branches of science and technology … in the fabrication of microfluidic
devices aimed at tissue culture… an advance in the liver tissue engineering field. However, due …

(Bio) fabrication of microfluidic devices and organs-on-a-chip

A Hrynevich, Y Li, G Cedillo-Servin, J Malda… - 3D Printing in …, 2023 - Elsevier
… OoC models, including skin, liver, and heart while further … lung and liver cells were seeded
into a silicon microfluidic chip … of the exact length and branching morphology of neuritis [49]. …

Design of a versatile microfluidic device for imaging precision-cut-tissue slices

N Rafiei, MG Moghadam, A Au, R Regeenes… - …, 2022 - iopscience.iop.org
… device to incubate and study liver slice tissues. Using 25 µl … The bottom layer where
the slice is trapped was fabricatedtissue, which contrasts with an earlier single ('non-branched') …

Recent progress of organ-on-a-chip towards cardiovascular diseases: advanced design, fabrication, and applications

H Wu, S Shi, Y Liu, Q Zhang, RHW Lam, CT Lim… - Biofabrication, 2023 - iopscience.iop.org
… devices, typically made of silicon and glass cannot be used in … , researchers began to use
micromachining methods to … and they also sprouted additional branches and recruited pre-…

[PDF][PDF] Design and Evaluation of Vascularizing Scaffolds Towards Multi-compartment Engineered Tissues

S Parkhideh - 2022 - repository.rice.edu
… and tissue-agnostic design, we designed and fabricated core-… of tissue engineering and
fabricate functional hearts, livers, … Thus, a hierarchical branching vascular system is needed. …

Fabrication of a porous three-dimensional scaffold with interconnected flow channels: co-cultured liver cells and in vitro hemocompatibility assessment

M Li, RR Khadim, M Nagayama, M Shinohara… - Applied Sciences, 2021 - mdpi.com
… stereolithography [1], deposition and layering [2], silicon micromachining [3], 3-D printing [4], …
not disrupt the 3-D branched flow channels. The fabricated PCL scaffolds were seeded with …