… lower potency than when injected simultaneously.6 Antibody … ISA-51, excellent systemic T
cell responses against melanoma-… of T cell responses to conserved T cell epitopes in multiple …

… ), aAVC-PROS therapy elicited multiple antigen-specific CD8+ T cells simultaneously. These
… as aAVC-PROS and verified the advantages of this vaccine in a cold tumor melanoma …

… simultaneously activate CD8 + and CD4 + T cell responses by combining MHC-I and MHC-II
epitopes into one long peptide antigen. … two long dual-epitope peptides from the melanoma …

… RONS simultaneously to oxidize the two melanoma-associated … These altered epitopes
may be involved in immune escape … [42] It is also known that single proteins or multi-peptide …

… with antigens (multi-peptide) of cancer patients including … class I restricted epitopes are
presented to T cells. In several … for the simultaneous expression of melanoma antigens. This …

… 369-377 ) and melanoma antigen recognized by T cells 1 (MART-… cells (DCs), facilitated the
co-delivery of antigen epitopes to … against tumor heterogeneity by simultaneously presenting …

… We have previously demonstrated that the simultaneous … -I restricted glycoprotein 100 epitope
(gp100) (melanoma antigen) on E2 … We observed approximately 2× CD8 T cells in spleens …

… they stimulate CD8 + T cells less effectively than their short epitope … First, we compared CD8
+ and CD4 + T cell responses … only CD8 + T cell responses but also CD4 + T cell responses …

… CD8 + T cells, without concurrent activation of CD4 + helper … ex vivo CD8 + T cell responses
in melanoma patients, it did … enhanced the epitope-specific T cell response. These findings …

… This study explored the efficacy of multi-peptide pulsing of … cells with DNA constructs encoding
tumor antigen epitopes [10… /NCL-specific T cells through concurrent stimulation of PBMCs …