Simultaneous edited MRS of GABA, glutathione, and ethanol

MG Saleh, M Wang, M Mikkelsen, SCN Hui… - NMR in …, 2020 - Wiley Online Library
… In this paper, simultaneous HERMES editing of GABA and GSH11 has been extended to
include orthogonal editing of EtOH without an increase in scan time or substantial loss in …

An evaluation of the reproducibility of 1H-MRS GABA and GSH levels acquired in healthy volunteers with J-difference editing sequences at varying echo times

JJ Prisciandaro, M Mikkelsen, MG Saleh… - Magnetic resonance …, 2020 - Elsevier
… , which enable the simultaneous measurement of ɣ-aminobutyric acid (GABA), the primary
inhibitory amino acid neurotransmitter in the central nervous system, and of glutathione (GSH)…

[HTML][HTML] Simultaneous quantification of GABA, Glx and GSH in the neonatal human brain using magnetic resonance spectroscopy

MY Lopez, AN Price, NAJ Puts, EJ Hughes… - Neuroimage, 2021 - Elsevier
edited-MRS acquisition. With this approach we report for the first time simultaneous GABA+, …
and Glutamate, and the protective role of the major antioxidant glutathione (GSH). Together, …

In vivo brain GSH: MRS methods and clinical applications

F Bottino, M Lucignani, A Napolitano, F Dellepiane… - Antioxidants, 2021 - mdpi.com
… metabolite (eg, GSH and GABA) or based on the acquisition of … edited detection allows for
GSH editing simultaneously with … 7 T MRS demonstrated increased levels of glutathione in the …

[PDF][PDF] … of Hadamard Encoding and Reconstruction of MEGA-Edited Spectroscopy (HERMES) for quantification of ɣ-aminobutyric acid (GABA) and glutathione (GSH)

D Rimbault - 2020 - open.uct.ac.za
… metabolites than GABA- or GSH-edited MEGA-PRESS. Our findings also showed that
simultaneous fitting … As a result, GABA and GSH MRS require the application of advanced spectral …

Importance of linear combination modeling for quantification of Glutathione and GABA levels using Hadamard-edited MRS

Y Song, HJ Zöllner, SCN Hui, G Oeltzschner… - bioRxiv, 2021 - biorxiv.org
… Thus simultaneous detection of GSH and GABA in a single HERMES experiment is a
promising approach for efficiently measuring two potential biomarkers of key disease processes. …

[HTML][HTML] Glutamate, GABA and glutathione in adults with persistent post-concussive symptoms

JM Joyce, LJ Mercier, M Stokoe, PL La, T Bell… - NeuroImage: Clinical, 2022 - Elsevier
… spectroscopy (MRS) methods at 3 Tesla, GABA and GSH … HERMES method to simultaneously
investigate GABA+ and … HERMES spectral editing method to measure GABA+ and GSH …

Signal enhancement of glutamine and glutathione by single-step spectral editing

L An, MF Araneta, M Victorino, J Shen - Journal of Magnetic Resonance, 2020 - Elsevier
… information for measuring GABA and the NAA singlet … -edit to simultaneously fit the three
spectra of different editing settings is hard to implement and not supported by widely used MRS

Glutamate measurements using edited MRS

MG Saleh, A Prescot, L Chang, C Cloak… - Magnetic resonance …, 2024 - Wiley Online Library
… γ-aminobutyric acid (GABA) and the antioxidant glutathione (GSH). Glu may … edited MRS.
We employed HERMES to deliver Glu, GABA, and GSH simultaneously in a single in vivo MRS

Effect of age on GABA+ and glutathione in a pediatric sample

MG Saleh, A Papantoni, M Mikkelsen… - American Journal …, 2020 - Am Soc Neuroradiology
… . Frequency and phase correction for multiplexed edited MRS of GABA and glutathione.
Magn … . Simultaneous editing of GABA and glutathione at 7T using semi‐LASER localization. …